The peroxisome proliferator-activated receptor (PPAR) family includes three transcription
factors: PPARα, PPARβ/δ, and PPARγ. PPAR are nuclear receptors activated by oxidised …

In the context of impact on human health, nitrite/nitrate and related nitrogen species such as
nitric oxide (NO) are a matter of increasing scientific controversy. An increase in the content …

Lipid peroxidation (LPO) has been shown to induce disturbance of membrane organization
and functional loss and modification of proteins and DNA bases, and it has been implicated …

Peroxynitrite is formed by the very fast reaction of nitric oxide and superoxide radicals, a
reaction that kinetically competes with other routes that chemically consume or physically …

Plasma medicine is an attractive new research area, but the principles of plasma
modification of biomolecules in aqueous solution remain elusive. In this study, we …

Global epidemiological studies show that chronic non-communicable diseases such as
atherosclerosis and metabolic disorders represent the leading cause of premature mortality …

Mammalian cells have evolved a unique strategy to protect themselves against oxidative
damage induced by reactive oxygen species (ROS). Especially, two transcription factors …

There has now been a great deal written about inorganic nitrate in both the popular press
and in scientific journals. Papers in the 1970s warned us that inorganic nitrate could …

Systemic lupus erythematosus (SLE) is a heterogeneous disease characterized by the
production of abnormal autoantibodies and immune complexes that can affect the organ and …

Nitric oxide participates in a wide array of physiological processes, ranging from
neurotransmission to precursor of cytotoxic effector molecules of the immune system …