To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …

Extracellular vesicles (EVs) are gaining increasing attention for diagnostic and therapeutic
applications in various diseases. These natural nanoparticles benefit from favorable safety …

There is a long-held consensus that several proteins are unique to small extracellular
vesicles (EVs), such as exosomes. However, recent studies have shown that several of …

RNA transfer via extracellular vesicles (EVs) influences cell phenotypes; however, lack of
information regarding biogenesis of RNA-containing EVs has limited progress in the field …

Background Therapeutic resistance occurs in most patients with multiple myeloma (MM).
One of the key mechanisms for MM drug resistance comes from the interaction between MM …

Extracellular vesicles (EVs) are nanosized vesicles with a lipid bilayer that are released from
cells of the cardiovascular system, and are considered important mediators of intercellular …

Diseases of the central nervous system (CNS) are challenging to treat, mainly due to the
blood-brain barrier (BBB), which restricts drugs in circulation from entering target regions in …

Growing evidence suggests that ceramides play an important role in the development of
atherosclerotic and valvular heart disease. Ceramides are biologically active sphingolipids …

Extracellular vesicles (EVs) are a heterogeneous group of membrane‐enclosed structures
produced by prokaryotic and eukaryotic cells. EVs carry a range of biological cargoes …

Diabetes mellitus (DM) is a chronic systemic disease with increasing prevalence globally.
An important aspect of diabetic pathogenesis is cellular crosstalk and information exchange …