Role of temperature in the decohesion of an elastic chain tethered to a substrate by onsite breakable links

G Florio, G Puglisi, S Giordano - Physical Review Research, 2020 - APS
We analyze the role of temperature in the rate-independent cohesion and decohesion
behavior of an elastic film, mimicked by a one-dimensional mass-spring chain, grounded to …

Thermal effects on fracture and the brittle-to-ductile transition

A Cannizzo, S Giordano - Physical Review E, 2023 - APS
The fracture behavior of brittle and ductile materials can be strongly influenced by thermal
fluctuations, especially in micro-and nanodevices as well as in rubberlike and biological …

Temperature controlled decohesion regimes of an elastic chain adhering to a fixed substrate by softening and breakable bonds

A Cannizzo, G Florio, G Puglisi… - Journal of Physics A …, 2021 - iopscience.iop.org
We study the rate-independent decohesion process for a chain linked to a substrate through
a series of breakable elements with a softening mechanism. Such an assumption describes …

Thermodynamics of small systems with conformational transitions: The case of two-state freely jointed chains with extensible units

M Benedito, S Giordano - The Journal of Chemical Physics, 2018 - pubs.aip.org
Several experimental methods are usually applied for stretching single molecules and
provide valuable insights about the static and dynamic responses induced by externally …

Isotensional and isometric force-extension response of chains with bistable units and Ising interactions

M Benedito, S Giordano - Physical Review E, 2018 - APS
The combination of bistability and cooperativity plays a crucial role in several biological and
artificial micro-and nanosystems. In particular, the exhaustive understanding of the …

Real-time mechanical characterization of DNA degradation under therapeutic X-rays and its theoretical modeling

G Perret, T Lacornerie, F Manca, S Giordano… - Microsystems & …, 2016 - nature.com
The killing of tumor cells by ionizing radiation beams in cancer radiotherapy is currently
based on a rather empirical understanding of the basic mechanisms and effectiveness of …

Spin variable approach for the statistical mechanics of folding and unfolding chains

S Giordano - Soft Matter, 2017 - pubs.rsc.org
The force–extension response of chains composed of bistable (or multistable) units strongly
depends on the applied boundary conditions. As a matter of fact, isotensional conditions …

Statistical Mechanics Approaches for Studying Temperature and Rate Effects in Multistable Systems

A Cannizzo, S Giordano - Symmetry, 2024 - mdpi.com
Systems with a multistable energy landscape are widespread in physics, biophysics,
technology, and materials science. They are strongly influenced by thermal fluctuations and …

Rate-dependent force–extension models for single-molecule force spectroscopy experiments

M Benedito, F Manca, PL Palla, S Giordano - Physical Biology, 2020 - iopscience.iop.org
Single-molecule force spectroscopy techniques allow for the measurement of several static
and dynamic features of macromolecules of biological origin. In particular, atomic force …

Full statistics of conjugated thermodynamic ensembles in chains of bistable units

M Benedito, F Manca, S Giordano - Inventions, 2019 - mdpi.com
The statistical mechanics and the thermodynamics of small systems are characterized by the
non-equivalence of the statistical ensembles. When concerning a polymer chain or an …