YAP/TAZ as master regulators in cancer: modulation, function and therapeutic approaches
S Piccolo, T Panciera, P Contessotto, M Cordenonsi - Nature cancer, 2023 - nature.com
Our understanding of the function of the transcriptional regulators YAP and TAZ (YAP/TAZ)
in cancer is advancing. In this Review, we provide an update on recent progress in YAP/TAZ …
in cancer is advancing. In this Review, we provide an update on recent progress in YAP/TAZ …
Protein design: From the aspect of water solubility and stability
Water solubility and structural stability are key merits for proteins defined by the primary
sequence and 3D-conformation. Their manipulation represents important aspects of the …
sequence and 3D-conformation. Their manipulation represents important aspects of the …
InterPro in 2022
T Paysan-Lafosse, M Blum, S Chuguransky… - Nucleic acids …, 2023 - academic.oup.com
Abstract The InterPro database (https://www. ebi. ac. uk/interpro/) provides an integrative
classification of protein sequences into families, and identifies functionally important …
classification of protein sequences into families, and identifies functionally important …
Introducing the bacterial and viral bioinformatics resource center (BV-BRC): a resource combining PATRIC, IRD and ViPR
Abstract The National Institute of Allergy and Infectious Diseases (NIAID) established the
Bioinformatics Resource Center (BRC) program to assist researchers with analyzing the …
Bioinformatics Resource Center (BRC) program to assist researchers with analyzing the …
RCSB Protein Data Bank (RCSB. org): delivery of experimentally-determined PDB structures alongside one million computed structure models of proteins from …
Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB
PDB), founding member of the Worldwide Protein Data Bank (wwPDB), is the US data center …
PDB), founding member of the Worldwide Protein Data Bank (wwPDB), is the US data center …
FerrDb V2: update of the manually curated database of ferroptosis regulators and ferroptosis-disease associations
N Zhou, X Yuan, Q Du, Z Zhang, X Shi… - Nucleic acids …, 2023 - academic.oup.com
Ferroptosis is a mode of regulated cell death characterized by iron-dependent accumulation
of lipid peroxidation. It is closely linked to the pathophysiological processes in many …
of lipid peroxidation. It is closely linked to the pathophysiological processes in many …
AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences
M Varadi, D Bertoni, P Magana, U Paramval… - Nucleic acids …, 2024 - academic.oup.com
Abstract The AlphaFold Database Protein Structure Database (AlphaFold DB,
https://alphafold. ebi. ac. uk) has significantly impacted structural biology by amassing over …
https://alphafold. ebi. ac. uk) has significantly impacted structural biology by amassing over …
AlphaFill: enriching AlphaFold models with ligands and cofactors
Artificial intelligence-based protein structure prediction approaches have had a
transformative effect on biomolecular sciences. The predicted protein models in the …
transformative effect on biomolecular sciences. The predicted protein models in the …
AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models
M Varadi, S Anyango, M Deshpande, S Nair… - Nucleic acids …, 2022 - academic.oup.com
Abstract The AlphaFold Protein Structure Database (AlphaFold DB, https://alphafold. ebi. ac.
uk) is an openly accessible, extensive database of high-accuracy protein-structure …
uk) is an openly accessible, extensive database of high-accuracy protein-structure …
EAACI molecular allergology user's guide 2.0
S Dramburg, C Hilger, AF Santos… - Pediatric Allergy and …, 2023 - Wiley Online Library
Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …