Updated review of advances in microRNAs and complex diseases: taxonomy, trends and challenges of computational models

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
Since the problem proposed in late 2000s, microRNA–disease association (MDA)
predictions have been implemented based on the data fusion paradigm. Integrating diverse …

Updated review of advances in microRNAs and complex diseases: towards systematic evaluation of computational models

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
Currently, there exist no generally accepted strategies of evaluating computational models
for microRNA-disease associations (MDAs). Though K-fold cross validations and case …

Application of machine learning in microbiology

K Qu, F Guo, X Liu, Y Lin, Q Zou - Frontiers in microbiology, 2019 - frontiersin.org
Microorganisms are ubiquitous and closely related to people's daily lives. Since they were
first discovered in the 19th century, researchers have shown great interest in …

A graph auto-encoder model for miRNA-disease associations prediction

Z Li, J Li, R Nie, ZH You, W Bao - Briefings in bioinformatics, 2021 - academic.oup.com
Emerging evidence indicates that the abnormal expression of miRNAs involves in the
evolution and progression of various human complex diseases. Identifying disease-related …

AMHMDA: attention aware multi-view similarity networks and hypergraph learning for miRNA–disease associations identification

Q Ning, Y Zhao, J Gao, C Chen, X Li… - Briefings in …, 2023 - academic.oup.com
In recent years, many experiments have proved that microRNAs (miRNAs) play a variety of
important regulatory roles in cells, and their abnormal expression can lead to the emergence …

GAERF: predicting lncRNA-disease associations by graph auto-encoder and random forest

QW Wu, JF Xia, JC Ni, CH Zheng - Briefings in bioinformatics, 2021 - academic.oup.com
Predicting disease-related long non-coding RNAs (lncRNAs) is beneficial to finding of new
biomarkers for prevention, diagnosis and treatment of complex human diseases. In this …

MDA-GCNFTG: identifying miRNA-disease associations based on graph convolutional networks via graph sampling through the feature and topology graph

Y Chu, X Wang, Q Dai, Y Wang, Q Wang… - Briefings in …, 2021 - academic.oup.com
Accurate identification of the miRNA-disease associations (MDAs) helps to understand the
etiology and mechanisms of various diseases. However, the experimental methods are …

SMALF: miRNA-disease associations prediction based on stacked autoencoder and XGBoost

D Liu, Y Huang, W Nie, J Zhang, L Deng - BMC bioinformatics, 2021 - Springer
Background Identifying miRNA and disease associations helps us understand disease
mechanisms of action from the molecular level. However, it is usually blind, time-consuming …

Predicting potential miRNA-disease associations by combining gradient boosting decision tree with logistic regression

S Zhou, S Wang, Q Wu, R Azim, W Li - Computational biology and …, 2020 - Elsevier
MicroRNAs (miRNAs) have been proved to play an indispensable role in many fundamental
biological processes, and the dysregulation of miRNAs is closely correlated with human …

Predicting miRNA-disease associations using an ensemble learning framework with resampling method

Q Dai, Z Wang, Z Liu, X Duan, J Song… - Briefings in …, 2022 - academic.oup.com
Motivation: Accumulating evidences have indicated that microRNA (miRNA) plays a crucial
role in the pathogenesis and progression of various complex diseases. Inferring disease …