Mesenchymal stromal cells for enhancing hematopoietic engraftment and treatment of graft-versus-host disease, hemorrhages and acute respiratory distress …

O Ringdén, G Moll, B Gustafsson… - Frontiers in …, 2022 - frontiersin.org
Mesenchymal stromal cells (MSCs) possess profound immunomodulatory and regenerative
properties that are of clinical use in numerous clinical indications with unmet medical need …

Current perspectives on mesenchymal stromal cell therapy for graft versus host disease

N Kadri, S Amu, E Iacobaeus, E Boberg… - Cellular & Molecular …, 2023 - nature.com
Graft versus host disease (GvHD) is the clinical condition in which bone marrow-derived
mesenchymal stromal cells (MSCs) have been most frequently studied. In this review, we …

Current status of clinical trials assessing mesenchymal stem cell therapy for graft versus host disease: a systematic review

Y Li, J Hao, Z Hu, YG Yang, Q Zhou, L Sun… - Stem Cell Research & …, 2022 - Springer
Background Graft-versus-host disease (GVHD) is a common fatal complication of
hematopoietic stem cell transplantation (HSCT), where steroids are used as a treatment …

Mesenchymal stem cells as a potential therapy for COVID-19

S Liu, D Peng, H Qiu, K Yang, Z Fu, L Zou - Stem cell research & therapy, 2020 - Springer
The outbreak of 2019 novel coronavirus disease (COVID-19) worldwide is becoming rapidly
a major concern. The number of severe cases has increased dramatically worldwide, while …

The immunomodulatory effects of mesenchymal stem cells on regulatory B cells

J Liu, Q Liu, X Chen - Frontiers in Immunology, 2020 - frontiersin.org
The therapeutic potential of mesenchymal stem cells (MSCs) has been investigated in many
preclinical and clinical studies. This potential is dominantly based on the …

Stem cell therapy for COVID‐19: Possibilities and challenges

MS Choudhery, DT Harris - Cell biology international, 2020 - Wiley Online Library
Since its eruption in China, novel coronavirus disease (COVID‐19) has been reported in
most of the countries and territories (> 200) of the world with∼ 18 million confirmed cases …

Mesenchymal stromal cells for treating steroid-resistant acute and chronic graft versus host disease: a multicenter compassionate use experience

MM Macías-Sánchez, C Morata-Tarifa… - Stem Cells …, 2022 - academic.oup.com
Graft versus host disease (GVHD) is a severe complication after allogenic hematopoietic cell
transplantation (HSCT). Several clinical trials have reported the use of mesenchymal stromal …

Second-line therapy for patients with steroid-refractory aGVHD: systematic review and meta-analysis of randomized controlled trials

C Luo, X Huang, L Wei, G Wu, Y Huang… - Frontiers in …, 2023 - frontiersin.org
Objective Steroids-refractory (SR) acute graft-versus-host disease (aGVHD) is a life-
threatening condition in patients undergoing allogeneic hematopoietic stem cell …

Management of chronic graft-vs.-host disease in children and adolescents with ALL: present status and model for a personalised management plan

A Sobkowiak-Sobierajska, C Lindemans… - Frontiers in …, 2022 - frontiersin.org
Herein we review current practice regarding the management of chronic graft-vs.-host
disease (cGvHD) in paediatric patients after allogeneic haematopoietic stem cell …

Tolerance to bone marrow transplantation: do mesenchymal stromal cells still have a future for acute or chronic Gvhd?

M Introna, J Golay - Frontiers in Immunology, 2020 - frontiersin.org
Mesenchymal Stromal Cells (MSCs) are fibroblast-like cells of mesodermal origin present in
many tissues and which have the potential to differentiate to osteoblasts, adipocytes and …