Age-dependent changes of the temporal order-causes and treatment

DG Gubin, D Weinert, TV Bolotnova - Current aging science, 2016 - ingentaconnect.com
This review summarizes current knowledge on deteriorations in temporal order with
advanced age. Changes of the overt rhythms will be described but also their putative causes …

Activity, sleep and ambient light have a different impact on circadian blood pressure, heart rate and body temperature rhythms

DG Gubin, D Weinert, SV Rybina… - Chronobiology …, 2017 - Taylor & Francis
The aim of the present study was to investigate the impact of endogenous and exogenous
factors for the expression of the daily rhythms of body temperature (BT), blood pressure (BP) …

Disrupted circadian rhythms of body temperature, heart rate and fasting blood glucose in prediabetes and type 2 diabetes mellitus

DG Gubin, AA Nelaeva, AE Uzhakova… - Chronobiology …, 2017 - Taylor & Francis
We report a progressive disruption of 24-h rhythms in fasting blood glucose (FBG), body
temperature (BT) and heart rate (HR) associated with metabolic dysfunction and the …

Circadian disruption and vascular variability disorders (VVD): Mechanisms linking aging, disease state and Arctic shift-work: Applications for Chronotherapy

DG Gubin, G Cornelissen, D Weinert… - World Heart …, 2013 - search.proquest.com
A fast growing body of evidence indicates that the circadian system is important for health. In
turn, desynchrony has been associated with the development of numerous age-related …

Factors that must be considered while solving the problem of adequate control of blood pressure

DG Gubin, G Cornelissen - Хрономедицинский журнал, 2019 - elibrary.ru
Many physicians still believe that single blood pressure (BP) measurements provide reliable
information for diagnostic purposes and treatment decisions. However, already 40 years …

Melatonin attenuates light-at-night effects on systolic blood pressure and body temperature but does not affect diastolic blood pressure and heart rate circadian …

D Gubin, D Weinert, SV Solovieva… - Biological Rhythm …, 2020 - Taylor & Francis
Aim of the present study is to assess whether 1.5 mg of exogenous melatonin provided
under modified CR in constant light (~ 400 lx) is capable to mimic effects of dark phase. Forty …

Circadian clock precision, health, and longevity

DG Gubin, SN Kolomeichuk, D Weinert - Хрономедицинский журнал, 2021 - elibrary.ru
An accurate circadian clock, associated with the precise intrinsic period, tau, can be linked
with a definite chronotype and health status. Exemplified by different animal species, and, as …

[PDF][PDF] Chronotheranostics and chronotherapy–frontiers for personalized medicine

D Gubin, D Weinert, G Cornélissen - J Chronomed, 2020 - researchgate.net
Ignoring the timing in the diagnostics and treatment of diseases becomes an anachronism.
The expression of most genes follows a circadian rhythm. Consequently, the existence of a …

[HTML][HTML] Сезонная периодичность мелатонинового обмена и гормонального статуса беременных в зависимости от пола плода

ТЛ Боташева, АВ Хлопонина… - … вестник Юга России, 2018 - cyberleninka.ru
Цель: выявление сезонных особенностей мелатонинового обмена и гормонального
статуса у беременных в зависимости от пола плода. Материалы и методы …

Temporal order deterioration and circadian disruption with age 1. Central and peripheral mechanisms

DG Gubin, D Weinert - Advances in Gerontology, 2015 - Springer
The review presents recent data on the mechanisms of temporal dynamics of aging
processes. The general principle of changes in multioscillatory network of phenotypic …