The concept of spatial confinement is the basis of cell positioning and guidance in in vitro
studies. In vivo, it reflects many situations faced during embryonic development. In vitro …

The function of a neural circuit can be determined by the following:(1) characteristics of
individual neurons composing the circuit,(2) their distinct connection structure, and (3) their …

Recent progress in the field of human induced pluripotent stem cells (iPSCs) has led to the
efficient production of human neuronal cell models for in vitro study. This has the potential to …

The development and application of micropatterning technology play a promising role in the
manipulation of biological substances and the exploration of life sciences at the microscale …

Alzheimer's disease is a severe neurodegenerative disorder of the brain, characterized by
beta-amyloid plaques, tau pathology, and cell death of cholinergic neurons, resulting in loss …

Spinal commissural axon navigation across the midline in the floor plate requires repulsive
forces from local Slit repellents. The long-held view is that Slits push growth cones forward …

Background The directionality analysis of the neurite outgrowths is an important
methodology in neuroscience, especially in determining the behavior of neurons grown on …

Summary Sensitization to Slits and Semaphorin (Sema) 3B floor plate repellents after
midline crossing is thought to be the mechanism expelling commissural axons …

L'impression protéique a initialement été utilisée pour reproduire et comprendre l'influence
de la matrice extracellulaire sur les cellules et certains de leurs composants. Au cours de la …

Understanding neuronal dynamics in normal and pathological conditions requires precise
electrophysiological measurements and detailed information about neuronal activity, as this …