Opioids form an important component of general anesthesia and perioperative analgesia.
Discharge opioid prescriptions are identified as a contributor for persistent opioid use and …

Background Excessive opioid prescribing after surgery has contributed to the current opioid
crisis; however, the value of prescribing opioids at surgical discharge remains uncertain. We …

Importance Prolonged opioid use after surgery may be associated with opioid dependency
and increased health care use. However, published studies have reported varying estimates …

Surgical procedures are key drivers of pain development and opioid utilization globally.
Various organizations have generated guidance on postoperative pain management …

Objective: The International Patterns of Opioid Prescribing study compares postoperative
opioid prescribing patterns in the United States (US) versus the rest of the world. Summary …

Background While persistent opioid use after surgery has been the subject of a large
number of studies, it is unknown how much variability in the definition of persistent use …

In the US, an opioid overdose crisis has emerged, attributable to over-prescription of opioid
analgesics, driven by aggressive marketing by pharmaceutical companies, followed by …

Objective To offer pragmatic, evidence-informed advice on nonsteroidal anti-inflammatory
drugs (NSAIDs) as first-line therapy after surgery. This companion to the American Academy …

Cardiac surgery is associated with significant postoperative pain, which complicates
recovery. The unique aspects of cardiac surgical pain include multiple sites of pain, initial …

In this article, we review controversies in assessing the risk of serious adverse effects
caused by administration of nonsteroidal anti-inflammatory drugs (NSAIDs). Our focus is …