[HTML][HTML] Impact of testosterone on Alzheimer's disease

VE Bianchi - The World Journal of Men's Health, 2022 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a neurodegenerative disease responsible for almost half of all
dementia cases in the world and progressively increasing. The etiopathology includes …

Molecular basis of Alzheimer's disease: focus on mitochondria

D Oliver, PH Reddy - Journal of Alzheimer's Disease, 2019 - content.iospress.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterized by
memory loss and multiple cognitive impairments. With the increased aging population, AD is …

An updated review: androgens and cognitive impairment in older men

Z Cai, H Li - Frontiers in Endocrinology, 2020 - frontiersin.org
Androgens are some of the most important sex hormones in men, and they maintain
important physiological activities in the human body. Cognitive impairment is one of the most …

Health risks of neonicotinoids chronic exposure and its association with glucose metabolism: A case-control study in rural China

L Wang, C Ma, D Wei, M Wang, Q Xu, J Wang… - Environmental …, 2023 - Elsevier
Since neonicotinoids (NNIs) are widely used around the world, they are extensively
distributed in the environment and frequently occurred in humans. This study was conducted …

Association of glucose fluctuations with sarcopenia in older adults with type 2 diabetes mellitus

N Ogama, T Sakurai, S Kawashima… - Journal of Clinical …, 2019 - mdpi.com
Type 2 diabetes mellitus accelerates loss of muscle mass and strength. Patients with
Alzheimer's disease (AD) also show these conditions, even in the early stages of AD. The …

[HTML][HTML] Machine learning and artificial intelligence in therapeutics and drug development life cycle

S Borkotoky, A Joshi, V Kaushik… - Drug Development Life …, 2022 - intechopen.com
In recent years, the pharmaceutical business has seen a considerable increase in data
digitization. With digitization, however, comes the challenge of obtaining, analyzing, and …

Caveolin: a new link between diabetes and AD

A Surguchov - Cellular and molecular neurobiology, 2020 - Springer
Alzheimer's disease (AD) and type 2 diabetes mellitus (T2D) are highly prevalent aging-
related diseases associated with significant morbidity and mortality. Patients with T2D have …

[HTML][HTML] Testosterone, cognitive decline and dementia in ageing men

BB Yeap, L Flicker - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
As men grow older, circulating testosterone concentrations decline, while prevalence of
cognitive impairment and dementia increase. Epidemiological studies of middle-aged and …

Molecular mechanisms of sex hormones in the development and progression of Alzheimer's disease

S Radaghdam, V Karamad, A Nourazarian… - Neuroscience …, 2021 - Elsevier
Alzheimer's disease (AD) is a form of brain disorder characterized by various pathological
changes in the brain. Numerous studies have shown that sex hormones are involved in the …

Anti-diabetic vanadyl complexes reduced Alzheimer's disease pathology independent of amyloid plaque deposition

Y Dong, T Stewart, Y Zhang, M Shi, C Tan, X Li… - Science China Life …, 2019 - Springer
Association of Alzheimer's disease (AD) with cerebral glucose hypometabolism, likely due to
impairments of insulin signaling, has been reported recently, with encouraging results when …