Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from
a binding site with unknown function to a firmly established major effector within the …

Connective tissue growth factor (CTGF), a multifunctional protein of the CCN family,
regulates cell proliferation, differentiation, adhesion, and a variety of other biological …

High-quality postoperative rehabilitation is the focus of most patients currently, and
hypertrophic scar (HS) greatly reduces the patient's quality of life due to the symptom of …

The AT1 receptor has mainly been associated with the pathological effects of the renin-
angiotensin system (RAS)(eg, hypertension, heart and kidney diseases), and constitutes a …

While normal, controlled wound-healing results in scars that are nearly imperceptible,
hypertrophic scars (HTS) and keloids are the result of an abnormal wound-healing process …

Hypertrophic scar (HS) and keloid are fibroproliferative disorders (FPDs) of the skin due to
aberrant wound healing, which cause disfigured appearance, discomfort, dysfunction …

Bacterial-associated wound infections are an obstacle for individuals and the medical
industry. Developing versatile, antibiotic-free therapies helps heal wounds more quickly and …

Background Annually, millions of people suffer from skin scars' psychological and physical
disadvantages. Pathologic scars prevention is challenging and requires developing feasible …

Renin-angiotensin system (RAS) components such as angiotensin II, angiotensin receptors
(AT 1 R and AT 2 R), and angiotensin-converting enzyme (ACE) are expressed in different …

N, N-dimethylglycine (DMG) is a naturally occurring compound being widely used as an oral
supplement to improve growth and physical performance. Thus far, its effects on human skin …