Connectome-based modelling of neurodegenerative diseases: towards precision medicine and mechanistic insight
JW Vogel, N Corriveau-Lecavalier… - Nature Reviews …, 2023 - nature.com
Neurodegenerative diseases are the most common cause of dementia. Although their
underlying molecular pathologies have been identified, there is substantial heterogeneity in …
underlying molecular pathologies have been identified, there is substantial heterogeneity in …
The functional role of the precuneus
NB Dadario, ME Sughrue - Brain, 2023 - academic.oup.com
Recent advancements in computational approaches and neuroimaging techniques have
refined our understanding of the precuneus. While previously believed to be largely a visual …
refined our understanding of the precuneus. While previously believed to be largely a visual …
The role of dopamine in NLRP3 inflammasome inhibition: Implications for neurodegenerative diseases
Abstract In the Central Nervous System (CNS), neuroinflammation orchestrated by microglia
and astrocytes is an innate immune response to counteract stressful and dangerous insults …
and astrocytes is an innate immune response to counteract stressful and dangerous insults …
The future of brain circuit-targeted therapeutics
SH Siddiqi, S Khosravani, JD Rolston… - …, 2024 - nature.com
The principle of targeting brain circuits has drawn increasing attention with the growth of
brain stimulation treatments such as transcranial magnetic stimulation (TMS), deep brain …
brain stimulation treatments such as transcranial magnetic stimulation (TMS), deep brain …
Regional precuneus cortical hyperexcitability in Alzheimer's disease patients
Objective Neuronal excitation/inhibition (E/I) imbalance is a potential cause of neuronal
network malfunctioning in Alzheimer's disease (AD), contributing to cognitive dysfunction …
network malfunctioning in Alzheimer's disease (AD), contributing to cognitive dysfunction …
Deciphering the clinico-radiological heterogeneity of dysexecutive Alzheimer's disease
Dysexecutive Alzheimer's disease (dAD) manifests as a progressive dysexecutive syndrome
without prominent behavioral features, and previous studies suggest clinico-radiological …
without prominent behavioral features, and previous studies suggest clinico-radiological …
Transcranial magnetic stimulation effects on cognitive enhancement in mild cognitive impairment and Alzheimer's disease: a systematic review and meta-analysis
Y Yan, M Tian, T Wang, X Wang, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Introduction Transcranial magnetic stimulation (TMS) is a non-invasive intervention that
holds promise for improving cognitive function in individuals with Alzheimer's disease (AD) …
holds promise for improving cognitive function in individuals with Alzheimer's disease (AD) …
Multimodal fusion of multiple rest fMRI networks and MRI gray matter via parallel multilink joint ICA reveals highly significant function/structure coupling in Alzheimer's …
In this article, we focus on estimating the joint relationship between structural magnetic
resonance imaging (sMRI) gray matter (GM), and multiple functional MRI (fMRI) intrinsic …
resonance imaging (sMRI) gray matter (GM), and multiple functional MRI (fMRI) intrinsic …
Transcranial alternating current stimulation (tACS) at gamma frequency: an up-and-coming tool to modify the progression of Alzheimer's Disease
ML De Paolis, I Paoletti, C Zaccone, F Capone… - Translational …, 2024 - Springer
The last decades have witnessed huge efforts devoted to deciphering the pathological
mechanisms underlying Alzheimer's Disease (AD) and to testing new drugs, with the recent …
mechanisms underlying Alzheimer's Disease (AD) and to testing new drugs, with the recent …
Longitudinal resting-state EEG in amyloid-positive patients along the Alzheimer's disease continuum: considerations for clinical trials
Background To enable successful inclusion of electroencephalography (EEG) outcome
measures in Alzheimer's disease (AD) clinical trials, we retrospectively mapped the …
measures in Alzheimer's disease (AD) clinical trials, we retrospectively mapped the …