Techniques for and challenges in reconstructing 3D genome structures from 2D chromosome conformation capture data

Z Li, S Portillo-Ledesma, T Schlick - Current Opinion in Cell Biology, 2023 - Elsevier
Chromosome conformation capture technologies that provide frequency information for
contacts between genomic regions have been crucial for increasing our understanding of …

ParticleChromo3D+: a web server for ParticleChromo3D algorithm for 3D chromosome structure reconstruction

D Vadnais, O Oluwadare - Current Issues in Molecular Biology, 2023 - mdpi.com
Understanding the three-dimensional (3D) structure of chromatin is invaluable for
researching how it functions. One way to gather this information is the chromosome …

Complementing Hi-C information for 3D chromatin reconstruction by ChromStruct

C Caudai, E Salerno - Frontiers in Bioinformatics, 2024 - frontiersin.org
A multiscale method proposed elsewhere for reconstructing plausible 3D configurations of
the chromatin in cell nuclei is recalled, based on the integration of contact data from Hi-C …