The interaction of tumor cells with platelets is a prerequisite for successful hematogenous
metastatic dissemination. Upon tumor cell arrival in the blood, tumor cells immediately …

Besides their function in limiting blood loss and promoting wound healing, experimental
evidence has highlighted platelets as active players in all steps of tumorigenesis including …

Platelets have long been recognized as key players in hemostasis and thrombosis;
however, growing evidence suggests that they are also significantly involved in cancer, the …

Evolving information has identified disease mechanisms and dysregulation of host biology
that might be targeted therapeutically in coronavirus disease 2019 (COVID-19). Thrombosis …

Extensive experimental evidence shows that platelets support tumour metastasis. The
activation of platelets and the coagulation system have a crucial role in the progression of …

Since its inception, the Hemoglobin, Albumin, Lymphocyte, Platelet Score (HALP) has
gained attention as a new prognostic biomarker to predict several clinical outcomes in a …

Malignancy affects the hemostatic system and the hemostatic system affects malignancy. In
cancer patients there are a number of coagulation abnormalities which provide the …

After recruitment to the wound bed, monocytes differentiate into macrophages. Macrophages
play a central role in all stages of wound healing and orchestrate the wound healing …

Wound healing is an evolutionarily conserved, complex, multicellular process that, in skin,
aims at barrier restoration. This process involves the coordinated efforts of several cell types …

Cancer-associated thrombocytosis has long been linked to poor clinical outcome, but the
underlying mechanism is enigmatic. We hypothesized that platelets promote malignancy …