Regulatory T cells (Tregs) are abundant in tumor tissues, raising a question of whether
immunosuppressive tumor-infiltrating Tregs (TI-Tregs) can be selectively depleted or …

Pathophysiology of Inflammatory Bowel Diseases Research on IBDs has identified disrupted
immune responses in the gastrointestinal mucosa and putative disruptions in the gut …

Infiltration of regulatory T (Treg) cells, an immunosuppressive population of CD4+ T cells,
into solid cancers represents a barrier to cancer immunotherapy. Chemokine receptors are …

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly
infectious respiratory virus which is responsible for the coronavirus disease 2019 (COVID …

Regulatory T cells (Treg cells) are a small subset of immune cells that are dedicated to
curbing excessive immune activation and maintaining immune homeostasis. Accordingly …

Regulatory T cells (Tregs) are important for the induction and maintenance of peripheral
tolerance therefore, they are key in preventing excessive immune responses and …

Regulatory T (Treg) cells expressing the transcription factor Foxp3 have a critical role in the
maintenance of immune homeostasis and prevention of autoimmunity. Recent advances in …

The success of immunotherapy in oncology underscores the vital role of the immune system
in cancer development. Regulatory T cells (Tregs) maintain a fine balance between …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Immune checkpoint blockers (ICBs) have failed in all phase III glioblastoma (GBM) trials.
Here, we show that regulatory T (Treg) cells play a key role in GBM resistance to ICBs in …