A review of the global climate change impacts, adaptation, and sustainable mitigation measures
Climate change is a long-lasting change in the weather arrays across tropics to polls. It is a
global threat that has embarked on to put stress on various sectors. This study is aimed to …
global threat that has embarked on to put stress on various sectors. This study is aimed to …
Therapeutic outcomes of isatin and its derivatives against multiple diseases: Recent developments in drug discovery
Isatin (1 H indole 2, 3-dione) is a heterocyclic, endogenous lead molecule recognized in
humans and different plants. The isatin nucleus and its derivatives are owed the attention of …
humans and different plants. The isatin nucleus and its derivatives are owed the attention of …
GC/MS Profiling, Anti-Collagenase, Anti-Elastase, Anti-Tyrosinase and Anti-Hyaluronidase Activities of a Stenocarpus sinuatus Leaves Extract
Today, skin care products and cosmetic preparations containing natural ingredients are
widely preferred by consumers. Therefore, many cosmetic brands are encouraged to offer …
widely preferred by consumers. Therefore, many cosmetic brands are encouraged to offer …
A mini review on isatin, an anticancer scaffold with potential activities against neglected tropical diseases (NTDs)
Isatin, chemically an indole-1 H-2, 3-dione, is recognised as one of the most attractive
therapeutic fragments in drug design and development. The template has turned out to be …
therapeutic fragments in drug design and development. The template has turned out to be …
Identification of sulphonamide-tethered N-((triazol-4-yl)methyl)isatin derivatives as inhibitors of SARS-CoV-2 main protease
SARS-CoV-2 pandemic in the end of 2019 led to profound consequences on global health
and economy. Till producing successful vaccination strategies, the healthcare sectors …
and economy. Till producing successful vaccination strategies, the healthcare sectors …
Development of novel isatin thiazolyl-pyrazoline hybrids as promising antimicrobials in MDR pathogens
Microbial Multidrug Resistance (MDR) is an emerging global crisis. Derivatization of natural
or synthetic scaffolds is among the most reliable strategies to search for and obtain novel …
or synthetic scaffolds is among the most reliable strategies to search for and obtain novel …
Development of Novel Isatin-Tethered Quinolines as Anti-Tubercular Agents against Multi and Extensively Drug-Resistant Mycobacterium tuberculosis
We describe the design and synthesis of two isatin-tethered quinolines series (Q6a–h and
Q8a–h), in connection with our research interest in developing novel isatin-bearing anti …
Q8a–h), in connection with our research interest in developing novel isatin-bearing anti …
[PDF][PDF] Comprehensive Investigation of the Potential of Hydrazine and its Derivatives for the Synthesis of Various Molecules with Biological Activity
This review paper provides a comprehensive and in-depth analysis of the versatile utility of
hydrazine as a precursor for the synthesis of several significant hydrazides and related …
hydrazine as a precursor for the synthesis of several significant hydrazides and related …
Tetrahydrobenzo [h] quinoline derivatives as a novel chemotype for dual antileishmanial-antimalarial activity graced with antitubercular activity: Design, synthesis and …
TM Ibrahim, G Abada, M Dammann, RM Maklad… - European Journal of …, 2023 - Elsevier
Derivatives with tetrahydrobenzo [h] quinoline chemotype were synthesized via one-pot
reactions and evaluated for their antileishmanial, antimalarial and antitubercular activities …
reactions and evaluated for their antileishmanial, antimalarial and antitubercular activities …
Novel 2-arylthiazolidin-4-one-thiazole hybrids with potent activity against Mycobacterium tuberculosis
DIA Othman, A Hamdi, MM Abdel-Aziz, SM Elfeky - Bioorganic Chemistry, 2022 - Elsevier
Abstract Substituted aldehydes, ethyl 2-(2-amino-thiazol-4-yl) acetate), and 2-
mercaptoacetic acid, in a three-component one-pot green synthetic approach afforded 2 …
mercaptoacetic acid, in a three-component one-pot green synthetic approach afforded 2 …