Timing of thyroid hormone action in the developing brain: clinical observations and experimental findings

RT Zoeller, J Rovet - Journal of neuroendocrinology, 2004 - Wiley Online Library
The original concept of the critical period of thyroid hormone (TH) action on brain
development was proposed to identify the postnatal period during which TH supplement …

General background on the hypothalamic-pituitary-thyroid (HPT) axis

RT Zoeller, SW Tan, RW Tyl - Critical reviews in toxicology, 2007 - Taylor & Francis
This article reviews the thyroid system, mainly from a mammalian standpoint. However, the
thyroid system is highly conserved among vertebrate species, so the general information on …

A mechanistic view of polybrominated diphenyl ether (PBDE) developmental neurotoxicity

LG Costa, R de Laat, S Tagliaferri, C Pellacani - Toxicology letters, 2014 - Elsevier
Polybrominated diphenyl ethers (PBDEs), extensively used in the past few decades as flame
retardants in a variety of consumer products, have become world-wide persistent …

Thyroid gland and brain: Enigma of Hashimoto's encephalopathy

LP Churilov, PA Sobolevskaia, YI Stroev - Best Practice & Research …, 2019 - Elsevier
The versatile clinical manifestations of the Hashimoto's chronic autoimmune thyroiditis often
include psycho-neurological disorders. Although hypothyroidism disturbs significantly the …

[PDF][PDF] Polybrominated diphenyl ether (PBDE) flame retardants: environmental contamination, human body burden and potential adverse health effects

LG Costa, G Giordano, S Tagliaferri, A Caglieri… - Acta …, 2008 - jeffreydachmd.com
Polybrominated diphenyl ethers (PBDEs) are an important class of flame retardants, widely
used in a variety of consumer products. In the past several years, PBDEs have become …

Hashimoto encephalopathy—still more questions than answers

M Waliszewska-Prosół, M Ejma - Cells, 2022 - mdpi.com
The normal function of the nervous system is conditioned by the undisturbed function of the
thyroid gland and its hormones. Comprehensive clinical manifestations, including …

Effects of experimentally induced maternal hypothyroidism and hyperthyroidism on the development of rat offspring: II—The developmental pattern of neurons in …

OM Ahmed, RG Ahmed, AW El-Gareib… - International Journal of …, 2012 - Elsevier
Excessive concentrations of free radicals in the developing brain may lead to neurons
maldevelopment and neurons damage and death. Thyroid hormones (THs) states play an …

Thyroid hormones affect neurogenesis in the dentate gyrus of adult rat

P Ambrogini, R Cuppini, P Ferri, C Mancini… - …, 2005 - karger.com
Thyroid hormones play a crucial role in new neuron production and maturation during brain
development. However, the knowledge about the involvement of these hormones on adult …

[PDF][PDF] Severe hyperthyroidism induces mitochondria‐mediated apoptosis in rat liver

G Upadhyay, R Singh, A Kumar, S Kumar… - …, 2004 - Wiley Online Library
Thyrotoxicosis may be associated with a variety of abnormalities of liver function. The
pathogenesis of hepatic dysfunction in thyrotoxicosis is unknown, but has been attributed to …

Thyroid hormones and the control of cell proliferation or cell differentiation: paradox or duality?

E Kress, J Samarut, M Plateroti - Molecular and cellular endocrinology, 2009 - Elsevier
Amphibian metamorphosis perfectly illustrates a key paradox: thyroid hormones control
diverse cellular processes depending on the tissue context. This point is also reinforced by a …