Development of polymeric nanoparticles for blood–brain barrier transfer—strategies and challenges
Neurological disorders such as Alzheimer's disease, stroke, and brain cancers are difficult to
treat with current drugs as their delivery efficacy to the brain is severely hampered by the …
treat with current drugs as their delivery efficacy to the brain is severely hampered by the …
Iron oxide nanoparticles for biomedical applications: a perspective on synthesis, drugs, antimicrobial activity, and toxicity
Medical applications and biotechnological advances, including magnetic resonance
imaging, cell separation and detection, tissue repair, magnetic hyperthermia and drug …
imaging, cell separation and detection, tissue repair, magnetic hyperthermia and drug …
Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: A combinational approach for enhanced delivery of nanoparticles
M Norouzi, V Yathindranath, JA Thliveris, BM Kopec… - Scientific reports, 2020 - nature.com
Although doxorubicin (DOX) is an effective anti-cancer drug with cytotoxicity in a variety of
different tumors, its effectiveness in treating glioblastoma multiforme (GBM) is constrained by …
different tumors, its effectiveness in treating glioblastoma multiforme (GBM) is constrained by …
Unique properties of surface-functionalized nanoparticles for bio-application: functionalization mechanisms and importance in application
This review tries to summarize the purpose of steadily developing surface-functionalized
nanoparticles for various bio-applications and represents a fascinating and rapidly growing …
nanoparticles for various bio-applications and represents a fascinating and rapidly growing …
[HTML][HTML] Magnetic iron oxide nanoparticles for brain imaging and drug delivery
Central nervous system (CNS) disorders affect as many as 1.5 billion people globally. The
limited delivery of most imaging and therapeutic agents into the brain is a major challenge …
limited delivery of most imaging and therapeutic agents into the brain is a major challenge …
Recent advances in theranostic polymeric nanoparticles for cancer treatment: A review
Nanotheranostics is fast-growing pharmaceutical technology for simultaneously monitoring
drug release and its distribution, and to evaluate the real time therapeutic efficacy through a …
drug release and its distribution, and to evaluate the real time therapeutic efficacy through a …
Superparamagnetic iron oxide nanoparticles conjugated with folic acid for dual target-specific drug delivery and MRI in cancer theranostics
Y Huang, K Mao, B Zhang, Y Zhao - Materials Science and Engineering: C, 2017 - Elsevier
Monodispersed SPIONs (superparamagnetic iron oxide nanoparticles) co-coated with PEG
and PEI polymers were prepared by an improved polyol method. To accomplish cancer …
and PEI polymers were prepared by an improved polyol method. To accomplish cancer …
Overcoming the blood–brain barrier: successes and challenges in developing nanoparticle-mediated drug delivery systems for the treatment of brain tumours
C Ferraris, R Cavalli, PP Panciani… - International journal of …, 2020 - Taylor & Francis
High-grade gliomas are still characterized by a poor prognosis, despite recent advances in
surgical treatment. Chemotherapy is currently practiced after surgery, but its efficacy is …
surgical treatment. Chemotherapy is currently practiced after surgery, but its efficacy is …
Progress in polymeric nano-medicines for theranostic cancer treatment
Cancer is a life-threatening disease killing millions of people globally. Among various
medical treatments, nano-medicines are gaining importance continuously. Many …
medical treatments, nano-medicines are gaining importance continuously. Many …
Transferrin: biology and use in receptor-targeted nanotherapy of gliomas
Gliomas constitute 80% of malignant brain tumors. The survival rate of patients diagnosed
with malignant gliomas is only 34.4%, as seen in both adults as well as children. The biggest …
with malignant gliomas is only 34.4%, as seen in both adults as well as children. The biggest …