Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved cellular
process capable of degrading various biological molecules (eg, protein, glycogen, lipids …

Alzheimer's disease (AD) is a complex neurodegenerative disease in the elderly and the
most common cause of human dementia. AD is characterized by accumulation of abnormal …

Ferroptosis is a form of regulated cell death triggered by lipid peroxidation after inhibition of
the cystine/glutamate antiporter system X c–. However, key regulators of system X c–activity …

Autophagy is an evolutionarily conserved catabolic mechanism, by which eukaryotic cells
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …

Autophagy is a process of self-degradation that enables the cell to survive when faced with
starvation or stressful conditions. The mechanistic target of rapamycin (mTOR), also known …

Autophagy is a catabolic process aimed at recycling cellular components and damaged
organelles in response to diverse conditions of stress, such as nutrient deprivation, viral …

Autophagy plays a key role in the maintenance of cellular homeostasis. In healthy cells,
such a homeostatic activity constitutes a robust barrier against malignant transformation …

Autophagy (self-eating) is a conserved cellular degradation process that plays important
roles in maintaining homeostasis and preventing nutritional, metabolic, and infection …

Significance: Autophagy is a highly conserved eukaryotic cellular recycling process.
Through the degradation of cytoplasmic organelles, proteins, and macromolecules, and the …

Autophagy in Human Health and Disease | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …