Recent Advances in Alkenyl sp2 C–H and C–F Bond Functionalizations: Scope, Mechanism, and Applications

MZ Lu, J Goh, M Maraswami, Z Jia, JS Tian… - Chemical …, 2022 - ACS Publications
Alkenes and their derivatives are featured widely in a variety of natural products,
pharmaceuticals, and advanced materials. Significant efforts have been made toward the …

Synthesis, reactions and application of chalcones: A systematic review

MA Shalaby, SA Rizk, AM Fahim - Organic & Biomolecular Chemistry, 2023 - pubs.rsc.org
Chalcones are a group of naturally occurring compounds that have biological effects that
include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone …

Applications of trisulfide radical anion S 3˙− in organic synthesis

P Song, W Rao, T Chivers, SY Wang - Organic Chemistry Frontiers, 2023 - pubs.rsc.org
The trisulfide radical anion S3˙− is well-known as the blue chromophore in ultramarines and
it has a versatile role in materials chemistry, especially in the redox chemistry of alkali metal …

Piperine: Chemistry and biology

J Han, S Zhang, J He, T Li - Toxins, 2023 - mdpi.com
Piperine is a plant-derived promising piperamide candidate isolated from the black pepper
(Piper nigrum L.). In the last few years, this natural botanical product and its derivatives have …

Synthesis of Deuterated (E)-Alkene through Xanthate-Mediated Hydrogen–Deuterium Exchange Reactions

J Li, J Li, X Ji, R He, Y Liu, Z Chen, Y Huang… - Organic …, 2021 - ACS Publications
Herein we have developed a reversible hydrogen–deuterium exchange reaction of
nonactivated olefins. By using EtOCS2K as a mediator, the H/D exchange reaction was …

Synthesis of 2-benzyl benzoxazoles and benzothiazoles via elemental sulfur promoted cyclization of styrenes with 2-nitrophenols and N, N-dialkyl-3-nitroanilines

TK Chau, NT Ho, TH Ho, AT Nguyen… - Organic & …, 2024 - pubs.rsc.org
Herein we report a method for affording 2-benzyl benzoxazoles from substituted styrenes
and 2-nitrophenols. The success of this method relies on the use of simple reagents, namely …

Three-Component Assembly of Dihydropyrrolo[3,4-e][1,3]thiazines from Elemental Sulfur, Maleimides, and 1,3,5-Triazinanes

WK Wang, FY Bao, ZW Shang, J Zheng… - Organic Letters, 2024 - ACS Publications
A three-component reaction for the synthesis of dihydropyrrolo [3, 4-e][1, 3] thiazines has
been developed. Elemental sulfur, maleimides, and 1, 3, 5-triazinanes are assembled …

Visible-Light Driven Synthesis of Vinyl Amines without Photocatalyst

K Pal, D Das, KG Ghosh… - The Journal of Organic …, 2024 - ACS Publications
We developed a visible-light-induced vinyl amination of activated alkenes using TMSN3 and
CsF through EDA complex formation under an oxygen atmosphere. Without light, the EDA …

Late‐Stage Amination of Drug‐Like Benzoic Acids: Access to Anilines and Drug Conjugates through Directed Iridium‐Catalyzed C− H Activation

E Weis, MJ Johansson… - Chemistry–A European …, 2021 - Wiley Online Library
The functionalization of C− H bonds, ubiquitous in drugs and drug‐like molecules,
represents an important synthetic strategy with the potential to streamline the drug‐discovery …

Regio-and stereo-selective synthesis of β-phenylthio enamides via intramolecular 1, 2-thiol migration

Y Zhuang, J Zhang, K Yang, G Bi, X Huang… - Organic Chemistry …, 2024 - pubs.rsc.org
An efficient and novel method for the synthesis of β-phenylthio enamides via intramolecular
1, 2-thiol migration has been developed. The preliminary experimental and computational …