Depression predisposes to medical illnesses and advances biological aging indicated by
shorter telomere length, accelerated brain aging and advanced epigenetic aging. Medical …

Neuropsychiatric symptoms (NPSs) are common in patients with Alzheimer's disease (AD)
and are associated with accelerated cognitive impairment and earlier deaths. This review …

Despite the lower prevalence of severe mood disorders in the elderly as compared to
younger adults, late-life depression and bipolar disorder (BD) are more strongly associated …

Alongside their function in primary haemostasis and thrombo-inflammation, platelets are
increasingly considered a bridge between mental, immunological and coagulation-related …

Late-life depression (LLD) is one of the most common mental disorders among the older
adults. Population aging, social stress, and the COVID-19 pandemic have significantly …

Depression is a risk factor for the development of Alzheimer's disease (AD), and the
presence of depressive symptoms significantly increases the conversion of mild cognitive …

Given the failure to develop disease-modifying therapies for Alzheimer's disease (AD),
strategies aiming at preventing or delaying the onset of the disease are being prioritized …

Background We evaluated the role of cortical amyloid deposition as a factor contributing to
memory dysfunction and increased risk of dementia associated with late-life depression …

Behavioral and psychological symptoms of dementia (BPSD) have been extensively studied
in dementia than its prodromal stage, known as mild cognitive impairment (MCI). A …

Antidepressants have modest efficacy in late-life depression (LLD), perhaps because
various neurobiologic processes compromise frontolimbic networks required for …