Mesenchymal Stem Cell‐derived Exosomes: Novel Therapeutic Approach for Inflammatory Bowel Diseases
C Tian, M Yang, H Xu, M Zhu, Y Zhang… - Stem cells …, 2023 - Wiley Online Library
As double membrane‐encapsulated nanovesicles (30‐150 nm), exosomes (Exos) shuttle
between different cells to mediate intercellular communication and transport active cargoes …
between different cells to mediate intercellular communication and transport active cargoes …
A systematic review and meta‐analysis of clinical trials assessing safety and efficacy of human extracellular vesicle‐based therapy
M Van Delen, J Derdelinckx, K Wouters… - Journal of …, 2024 - Wiley Online Library
Nowadays, it has become clear that extracellular vesicles (EVs) are not a cellular waste
disposal vesicle but are an essential part of an intercellular communication system. Besides …
disposal vesicle but are an essential part of an intercellular communication system. Besides …
[HTML][HTML] Adipose tissue-derived mesenchymal stem cell-derived exosomes promote wound healing and tissue regeneration
Wound healing is a complex process involving cell proliferation, migration, and extracellular
matrix (ECM) remodeling. Extracellular vesicles (EVs) or exosomes derived from adipose …
matrix (ECM) remodeling. Extracellular vesicles (EVs) or exosomes derived from adipose …
Safety and efficacy of injection of human placenta mesenchymal stem cells derived exosomes for treatment of complex perianal fistula in non‐Crohn's cases: Clinical …
Background and Aim A perianal fistula is an abnormal tract that connects anal canal to skin.
Current medical and surgical interventions have a high failure rate particularly in complex …
Current medical and surgical interventions have a high failure rate particularly in complex …
[HTML][HTML] Exosome-based crosstalk in glaucoma pathogenesis: a focus on oxidative stress and neuroinflammation
L Wang, X Wei - Frontiers in Immunology, 2023 - frontiersin.org
Exosomes are membrane-bound tiny particles that are released by all live cells that contain
multiple signal molecules and extensively participate in numerous normal physical activities …
multiple signal molecules and extensively participate in numerous normal physical activities …
Double‐Layer Asymmetric Porous Mesh with Dynamic Mechanical Support Properties Enables Efficient Single‐Stage Repair of Contaminated Abdominal Wall Defect
F Tang, D Miao, R Huang, B Zheng, Y Yu… - Advanced …, 2024 - Wiley Online Library
Contamination tolerance and long‐term mechanical support are the two critical properties of
meshes for contaminated abdominal wall defect repair. However, biological meshes with …
meshes for contaminated abdominal wall defect repair. However, biological meshes with …
Exosomes for angiogenesis induction in ischemic disorders
K Moeinabadi‐Bidgoli, M Rezaee… - Journal of cellular …, 2023 - Wiley Online Library
Ischaemic disorders are leading causes of morbidity and mortality worldwide. While the
current therapeutic approaches have improved life expectancy and quality of life, they are …
current therapeutic approaches have improved life expectancy and quality of life, they are …
[HTML][HTML] A roadmap from research to clinical testing of mesenchymal stromal cell exosomes in the treatment of psoriasis
The most clinically trialed cells, mesenchymal stromal cells (MSCs), are now known to
mainly exert their therapeutic activity through paracrine secretions, which include exosomes …
mainly exert their therapeutic activity through paracrine secretions, which include exosomes …
Engineered stem cell-based strategy: A new paradigm of next-generation stem cell product in regenerative medicine
H Han, BT Chen, Y Liu, Y Wang, L Xing, H Wang… - Journal of Controlled …, 2024 - Elsevier
Stem cells have garnered significant attention in regenerative medicine owing to their
abilities of multi-directional differentiation and self-renewal. Despite these encouraging …
abilities of multi-directional differentiation and self-renewal. Despite these encouraging …
[HTML][HTML] Advances in the application of extracellular vesicles derived from three-dimensional culture of stem cells
W Chen, P Wu, C Jin, Y Chen, C Li, H Qian - Journal of …, 2024 - Springer
Stem cells (SCs) have been used therapeutically for decades, yet their applications are
limited by factors such as the risk of immune rejection and potential tumorigenicity …
limited by factors such as the risk of immune rejection and potential tumorigenicity …