A review of reward processing and motivational impairment in schizophrenia

GP Strauss, JA Waltz, JM Gold - Schizophrenia bulletin, 2014 - academic.oup.com
This article reviews and synthesizes research on reward processing in schizophrenia, which
has begun to provide important insights into the cognitive and neural mechanisms …

A transdiagnostic review of negative symptom phenomenology and etiology

GP Strauss, AS Cohen - Schizophrenia bulletin, 2017 - academic.oup.com
In the DSM5, negative symptoms are 1 of the 5 core dimensions of psychopathology
evaluated for schizophrenia. However, negative symptoms are not pathognomonic—they …

How much of reinforcement learning is working memory, not reinforcement learning? A behavioral, computational, and neurogenetic analysis

AGE Collins, MJ Frank - European Journal of Neuroscience, 2012 - Wiley Online Library
Instrumental learning involves corticostriatal circuitry and the dopaminergic system. This
system is typically modeled in the reinforcement learning (RL) framework by incrementally …

Mechanisms underlying motivational deficits in psychopathology: similarities and differences in depression and schizophrenia

DM Barch, D Pagliaccio, K Luking - Behavioral neuroscience of motivation, 2016 - Springer
Motivational and hedonic impairments are core aspects of a variety of types of
psychopathology. These impairments cut across diagnostic categories and may be critical to …

[HTML][HTML] Striatal dysfunction during reversal learning in unmedicated schizophrenia patients

F Schlagenhauf, QJM Huys, L Deserno, MA Rapp… - Neuroimage, 2014 - Elsevier
Subjects with schizophrenia are impaired at reinforcement-driven reversal learning from as
early as their first episode. The neurobiological basis of this deficit is unknown. We obtained …

[HTML][HTML] The prediction-error hypothesis of schizophrenia: new data point to circuit-specific changes in dopamine activity

SJ Millard, CE Bearden, KH Karlsgodt… - …, 2022 - nature.com
Schizophrenia is a severe psychiatric disorder affecting 21 million people worldwide. People
with schizophrenia suffer from symptoms including psychosis and delusions, apathy …

Interactions among working memory, reinforcement learning, and effort in value-based choice: A new paradigm and selective deficits in schizophrenia

AGE Collins, MA Albrecht, JA Waltz, JM Gold… - Biological …, 2017 - Elsevier
Background When studying learning, researchers directly observe only the participants'
choices, which are often assumed to arise from a unitary learning process. However, a …

Decision-making in schizophrenia: A predictive-coding perspective

P Sterzer, M Voss, F Schlagenhauf, A Heinz - NeuroImage, 2019 - Elsevier
Dysfunctional decision-making has been implicated in the positive and negative symptoms
of schizophrenia. Decision-making can be conceptualized within the framework of …

The neural underpinnings of cognitive flexibility and their disruption in psychotic illness

JA Waltz - Neuroscience, 2017 - Elsevier
Schizophrenia (SZ) has long been associated with a variety of cognitive deficits, including
reduced cognitive flexibility. More recent findings, however, point to tremendous inter …

Predictive processing, source monitoring, and psychosis

JD Griffin, PC Fletcher - Annual review of clinical psychology, 2017 - annualreviews.org
A comprehensive understanding of psychosis requires models that link multiple levels of
explanation: the neurobiological, the cognitive, the subjective, and the social. Until we can …