Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …

Oxidative stress and chronic inflammation are known to be associated with the development
of metabolic diseases, including diabetes. Oxidative stress, an imbalance between oxidative …

Prevalence of diabetes, a serious public health problem is rapidly increasing worldwide.
Type-2 diabetes is the common form of diabetes characterized by insulin resistance and …

Vitamin D deficiency has been linked to the onset of diabetes. This review summarizes the
role of Vitamin D in maintaining the normal release of insulin by the pancreatic beta cells (β …

Oxidative stress (OS) is primarily caused by the formation of free radicals and reactive
oxygen species; it is considered as one of the prominent factors in slowing down and …

The prevalence of diabetes mellitus is rising all over the world. Uncontrolled state of
hyperglycemia due to defects in insulin secretion/action leads to a variety of complications …

Type 2 diabetes mellitus (T2DM) is a complex, chronic and progressive metabolic disease,
which is characterized by relative insulin deficiency, insulin resistance, and high glucose …

Alzheimer disease (AD) is the most common form of dementia among the elderly and is
characterized by progressive loss of memory and cognition. Epidemiological data show that …

A growing body of evidence links type-2 diabetes (T2D) with dementia and
neurodegenerative diseases such as Alzheimer's disease (AD). AD is the most common …