Neuropathic pain is a disease of the somatosensory system that is characterized by tingling,
burning, and/or shooting pain. Medication is often the primary treatment, but it can be costly …

Oxidative stress can be induced by various stimuli and altered in certain conditions,
including exercise and pain. Although many studies have investigated oxidative stress in …

Peripheral neuropathy is a widespread and potentially incapacitating pathological condition
that encompasses more than 100 different forms and manifestations of nerve damage. The …

Physical activity has become a first-line treatment in rehabilitation settings for individuals
with chronic pain. However, research has only recently begun to elucidate the mechanisms …

Diabetic peripheral neuropathy (DPN) occurs in more than 50% of people with diabetes and
is an important risk factor for skin breakdown, amputation, and reduced physical mobility (ie …

Diabetes is the 4th most common disease affecting the world's population. It is accompanied
by many complications that deteriorate the quality of life. Painful diabetic neuropathy (PDN) …

The utilization of physical activity as a therapeutic tool is rapidly growing in the medical
community and the role exercise may offer in the alleviation of painful disease states is an …

Much evidence from pain patients and animal models shows that chronic pain does not exist
in a vacuum but has varied comorbidities and far-reaching consequences. Patients with long …

Spinal cord injury (SCI) induces neuropathic pain that is refractory to treatment. Central and
peripheral immune responses to SCI play critical roles in pain development. Although …

Purpose Diabetic peripheral neuropathy (DPN) leads to decreased sole sensation and
balance disorder, all of which increase the risk of falls and socioeconomic costs. Since the …