The potential preventive and therapeutic roles of NSAIDs in prostate cancer

H Maghsoudi, F Sheikhnia, P Sitarek, N Hajmalek… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer is a serious health problem for men around the world, and
it is often caused by inflammation in the prostate gland. The authors of this article explore …

[HTML][HTML] Evaluations of aqueous humor protein markers in different types of glaucoma

H Chen, G Zheng, H Chen, L Li, Z Xu, L Xu - Medicine, 2022 - journals.lww.com
Evaluations of aqueous humor protein markers in different ty... : Medicine Evaluations of
aqueous humor protein markers in different types of glaucoma : Medicine Log in or Register Get …

In silico molecular docking, ADME study and synthesis of new 1,3-diazetidin-2-one derivatives with high anti-proliferative activity

FH Abdulredha, MF Mahdi, AK Khan - F1000Research, 2023 - f1000research.com
Background: Cancer and inflammation are strongly connected; tumor growth and spread are
also greatly influenced by inflammation. Nitrogen-based heterocycle analogs are excellent …

Mefenamic acid exhibits antitumor activity against osteosarcoma by impeding cell growth and prompting apoptosis in human osteosarcoma cells and xenograft mice …

J Ye, T Chang, X Zhang, D Wei, Y Wang - Chemico-Biological Interactions, 2024 - Elsevier
The study investigates the anticancer activity of mefenamic acid against osteosarcoma,
shedding light on its underlying mechanisms and therapeutic potential. Mefenamic acid …

Exploring the potential of new mefenamic acid derivatives as α-glucosidase inhibitors: Structure-activity relationship, in-vitro and in-silico studies

S Daud, W Rehman, A Sardar, MM Alanazi… - Journal of Molecular …, 2024 - Elsevier
The current study outlines the synthesis of 28 new heterocyclic compounds derived from
mefenamic acid, as well as an investigation of their therapeutic potential beyond traditional …

The cytotoxic activity evaluation of an arylhydrazone derivative of mefenamic acid on HEPG2 liver cancer cells and normal gingival HGF cells

T Hojatipour, S Pashapour, A Almasirad, Z Mousavi - Gene Reports, 2023 - Elsevier
Background and objective Although the anti-cancer effects of nonsteroidal anti-inflammatory
drugs have been shown in many studies, the results are still controversial. This study aimed …

L‐lysine Janus Dendrimer Conjugate with Naproxen and Mefenamic Acid and its Anticancer Activity

IO Castillo‐Rodríguez, I Saavedra‐González… - …, 2024 - Wiley Online Library
Dendritic architectures have potential use as excellent carriers for drug delivery due to their
multifunctionality, biopermeability, and biodegradability properties. Furthermore, their …

[PDF][PDF] The Potential Preventive and Therapeutic Roles of NSAIDs in Prostate Cancer. Cancers 2023, 15, 5435

H Maghsoudi, F Sheikhnia, P Sitarek, N Hajmalek… - 2023 - academia.edu
Prostate cancer (PC) is the second most common type of cancer and the leading cause of
death among men worldwide. Preventing the progression of cancer after treatments such as …

Functional role of novel indomethacin derivatives for the treatment of hepatocellular carcinoma through inhibition of platelet-derived growth factor

S Patel, P Nanavati, J Sharma, V Chavda… - Archives of Medical …, 2021 - Elsevier
Background Several studies suggested anticancer potential of NSAIDs. Therefore, we aimed
to evaluate novel indomethacin derivatives for the treatment of hepatocellular carcinoma …

Preparation, Characterization, of Some Oxadiazol Derivatives Prepared from Different Carboxylic Acids

SA Yousif - Baghdad Science Journal, 2024 - bsj.uobaghdad.edu.iq
A series of Mefenamic acid derivatives were designed and synthesized and the products
were characterized spectroscopically using FT-IR, 1H NMR, and 13C NMR techniques …