The role of TREX in gene expression and disease
CG Heath, N Viphakone, SA Wilson - Biochemical Journal, 2016 - portlandpress.com
TRanscription and EXport (TREX) is a conserved multisubunit complex essential for
embryogenesis, organogenesis and cellular differentiation throughout life. By linking …
embryogenesis, organogenesis and cellular differentiation throughout life. By linking …
Cryo-EM structure of the yeast TREX complex and coordination with the SR-like protein Gbp2
Y Xie, BP Clarke, YJ Kim, AL Ivey, PS Hill, Y Shi, Y Ren - Elife, 2021 - elifesciences.org
The evolutionarily conserved TRanscript-EXport (TREX) complex plays central roles during
mRNP (messenger ribonucleoprotein) maturation and export from the nucleus to the …
mRNP (messenger ribonucleoprotein) maturation and export from the nucleus to the …
Genome-wide analysis and stress-responsive expression of CCCH zinc finger family genes in Brassica rapa
B Pi, X He, Y Ruan, JC Jang, Y Huang - BMC Plant Biology, 2018 - Springer
Background Ubiquitous CCCH nucleic acid-binding motif is found in a wide-variety of
organisms. CCCH genes are involved in plant developmental processes and biotic and …
organisms. CCCH genes are involved in plant developmental processes and biotic and …
hLARP7 C-terminal domain contains an xRRM that binds the 3΄ hairpin of 7SK RNA
CD Eichhorn, R Chug, J Feigon - Nucleic acids research, 2016 - academic.oup.com
The 7SK small nuclear ribonucleoprotein (snRNP) sequesters and inactivates the positive
transcription elongation factor b (P-TEFb), an essential eukaryotic mRNA transcription factor …
transcription elongation factor b (P-TEFb), an essential eukaryotic mRNA transcription factor …
6-Gingerol attenuates subarachnoid hemorrhage-induced early brain injury via GBP2/PI3K/AKT pathway in the rat model
H Tang, C Shao, X Wang, Y Cao, Z Li, X Luo… - Frontiers in …, 2022 - frontiersin.org
Numerous studies have elucidated the neuroprotective effect of 6-gingerol in central
nervous system diseases. However, the potential role and mechanism of 6-gingerol on early …
nervous system diseases. However, the potential role and mechanism of 6-gingerol on early …
Insight into the Structural Basis for Dual Nucleic Acid—Recognition by the Scaffold Attachment Factor B2 Protein
SM Korn, J Von Ehr, K Dhamotharan, JN Tants… - International Journal of …, 2023 - mdpi.com
The family of scaffold attachment factor B (SAFB) proteins comprises three members and
was first identified as binders of the nuclear matrix/scaffold. Over the past two decades …
was first identified as binders of the nuclear matrix/scaffold. Over the past two decades …
Plasmodium falciparum GBP2 Is a Telomere-Associated Protein That Binds to G-Quadruplex DNA and RNA
J Edwards-Smallbone, AL Jensen… - Frontiers in Cellular …, 2022 - frontiersin.org
In the early-diverging protozoan parasite Plasmodium, few telomere-binding proteins have
been identified and several are unique. Plasmodium telomeres, like those of most …
been identified and several are unique. Plasmodium telomeres, like those of most …
RGG-motif containing mRNA export factor Gbp2 acts as a translation repressor
G Poornima, G Srivastava, B Roy, IA Kuttanda… - RNA biology, 2021 - Taylor & Francis
Complex cascades of RNA-binding proteins regulate the mRNA metabolism and influence
gene expression. Several distinct proteins act at different stages of mRNA life cycle. SR …
gene expression. Several distinct proteins act at different stages of mRNA life cycle. SR …
Sgh1, an SR-like Protein, Is Involved in Fungal Development, Plant Infection, and Pre-mRNA Processing in Fusarium graminearum
G Wang, P Sun, Z Sun, J Zhu, D Yu, Z Tang, Z Wang… - Journal of Fungi, 2022 - mdpi.com
Serine/arginine (SR) proteins are essential pre-mRNA splicing factors in eukaryotic
organisms. Our previous studies have shownthat the unique SR-specific protein kinase Srk1 …
organisms. Our previous studies have shownthat the unique SR-specific protein kinase Srk1 …
The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition
E Franco-Echevarría, N González-Polo… - Nucleic Acids …, 2017 - academic.oup.com
Transcription termination of non-coding RNAs is regulated in yeast by a complex of three
RNA binding proteins: Nrd1, Nab3 and Sen1. Nrd1 is central in this process by interacting …
RNA binding proteins: Nrd1, Nab3 and Sen1. Nrd1 is central in this process by interacting …