TRanscription and EXport (TREX) is a conserved multisubunit complex essential for
embryogenesis, organogenesis and cellular differentiation throughout life. By linking …

The evolutionarily conserved TRanscript-EXport (TREX) complex plays central roles during
mRNP (messenger ribonucleoprotein) maturation and export from the nucleus to the …

Background Ubiquitous CCCH nucleic acid-binding motif is found in a wide-variety of
organisms. CCCH genes are involved in plant developmental processes and biotic and …

The 7SK small nuclear ribonucleoprotein (snRNP) sequesters and inactivates the positive
transcription elongation factor b (P-TEFb), an essential eukaryotic mRNA transcription factor …

Numerous studies have elucidated the neuroprotective effect of 6-gingerol in central
nervous system diseases. However, the potential role and mechanism of 6-gingerol on early …

The family of scaffold attachment factor B (SAFB) proteins comprises three members and
was first identified as binders of the nuclear matrix/scaffold. Over the past two decades …

In the early-diverging protozoan parasite Plasmodium, few telomere-binding proteins have
been identified and several are unique. Plasmodium telomeres, like those of most …

Complex cascades of RNA-binding proteins regulate the mRNA metabolism and influence
gene expression. Several distinct proteins act at different stages of mRNA life cycle. SR …

Serine/arginine (SR) proteins are essential pre-mRNA splicing factors in eukaryotic
organisms. Our previous studies have shownthat the unique SR-specific protein kinase Srk1 …

Transcription termination of non-coding RNAs is regulated in yeast by a complex of three
RNA binding proteins: Nrd1, Nab3 and Sen1. Nrd1 is central in this process by interacting …