Alternative splicing of eukaryotic transcripts is a mechanism that enables cells to generate
vast protein diversity from a limited number of genes. The mechanisms and outcomes of …

Epithelial-to-mesenchymal transition (EMT) is associated with metastasis formation as well
as with generation and maintenance of cancer stem cells. In this way, EMT contributes to …

Alternative splicing (AS) is one crucial step of gene expression that must be tightly regulated
during neurodevelopment. However, the precise timing of developmental splicing switches …

Cancer is a complex disease that involves aberrant gene expression regulation.
Discriminating the modified expression patterns driving tumor biology from the many that …

Alternative splicing is crucial for diverse cellular, developmental, and pathological
processes. However, the full networks of factors that control individual splicing events are …

RNA splicing is a major contributor to total transcriptome complexity; however, the functional
role and regulation of splicing in heart failure remain poorly understood. Here, we used a …

The Rbfox genes encode an ancient family of sequence‐specific RNA binding proteins
(RBPs) that are critical developmental regulators in multiple tissues including skeletal …

Alternative splicing, a fundamental step in gene expression, is deregulated in many
diseases. Splicing factors (SFs), which regulate this process, are up-or down regulated or …

Insulin secretion is a tightly regulated process that is vital for maintaining blood glucose
homeostasis. Although the molecular components of insulin granule trafficking and secretion …

Embryonic myogenesis is a temporally and spatially regulated process that generates
skeletal muscle of the trunk and limbs. During this process, mononucleated myoblasts …