[HTML][HTML] Current applications and future perspective of CRISPR/Cas9 gene editing in cancer

SW Wang, C Gao, YM Zheng, L Yi, JC Lu, XY Huang… - Molecular cancer, 2022 - Springer
Clustered regularly interspaced short palindromic repeats (CRISPR) system provides
adaptive immunity against plasmids and phages in prokaryotes. This system inspires the …

Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Size-Controlled Synthesis of Sub-10-nanometer Citrate-Stabilized Gold Nanoparticles and Related Optical Properties.

J Piella, NG Bastus, V Puntes - Chemistry of Materials, 2016 - ACS Publications
Highly monodisperse, biocompatible and functionalizable sub-10-nm citrate-stabilized gold
nanoparticles (Au NPs) have been synthesized following a kinetically controlled seeded …

Gold nanoparticles in biomedical applications: recent advances and perspectives

L Dykman, N Khlebtsov - Chemical Society Reviews, 2012 - pubs.rsc.org
Gold nanoparticles (GNPs) with controlled geometrical, optical, and surface chemical
properties are the subject of intensive studies and applications in biology and medicine. To …

Size-dependent protein–nanoparticle interactions in citrate-stabilized gold nanoparticles: the emergence of the protein corona

J Piella, NG Bastús, V Puntes - Bioconjugate chemistry, 2017 - ACS Publications
Surface modifications of highly monodisperse citrate-stabilized gold nanoparticles (AuNPs)
with sizes ranging from 3.5 to 150 nm after their exposure to cell culture media …

Kinetically controlled seeded growth synthesis of citrate-stabilized gold nanoparticles of up to 200 nm: size focusing versus Ostwald ripening

NG Bastús, J Comenge, V Puntes - Langmuir, 2011 - ACS Publications
Monodisperse citrate-stabilized gold nanoparticles with a uniform quasi-spherical shape of
up to∼ 200 nm and a narrow size distribution were synthesized following a kinetically …

The in vitro and in vivo toxicity of gold nanoparticles

YP Jia, BY Ma, XW Wei, ZY Qian - Chinese Chemical Letters, 2017 - Elsevier
Gold nanoparticles, owing to their unique physicochemical and optical properties, well-
established synthetic methods and easy modifications, have been widely used in biomedical …

[HTML][HTML] Revisiting 30 years of biofunctionalization and surface chemistry of inorganic nanoparticles for nanomedicine

J Conde, JT Dias, V Grazú, M Moros… - Frontiers in …, 2014 - frontiersin.org
In the last 30 years we have assisted to a massive advance of nanomaterials in material
science. Nanomaterials and structures, in addition to their small size, have properties that …

Gold Nanoparticles as a Vaccine Platform: Influence of Size and Shape on Immunological Responses in Vitro and in Vivo

K Niikura, T Matsunaga, T Suzuki, S Kobayashi… - ACS …, 2013 - ACS Publications
This paper demonstrates how the shape and size of gold nanoparticles (AuNPs) affect
immunological responses in vivo and in vitro for the production of antibodies for West Nile …

Surface modification, functionalization and bioconjugation of colloidal inorganic nanoparticles

RA Sperling, WJ Parak - Philosophical Transactions of …, 2010 - royalsocietypublishing.org
Inorganic colloidal nanoparticles are very small, nanoscale objects with inorganic cores that
are dispersed in a solvent. Depending on the material they consist of, nanoparticles can …