There is an enormous global public health burden due to antimicrobial-resistant (AMR)
Klebsiella pneumoniae high-risk clones. K. pneumoniae ST307 and ST147 are recent …

The emergence of carbapenem-resistant Gram-negative pathogens poses a serious threat
to public health worldwide. In particular, the increasing prevalence of carbapenem-resistant …

Escherichia coli sequence type 131 (ST131) and Klebsiella pneumoniae ST258 emerged in
the 2000s as important human pathogens, have spread extensively throughout the world …

Klebsiella pneumoniae carbapenemases (KPCs) were originally identified in the USA in
1996. Since then, these versatile β-lactamases have spread internationally among Gram …

The management of infections due to Klebsiella pneumoniae has been complicated by the
emergence of antimicrobial resistance, especially to carbapenems. Resistance to …

Introduced in the 1980s, carbapenem antibiotics have served as the last line of defense
against multidrug‐resistant Gram‐negative organisms. Over the last decade, carbapenem …

Carbapenemase-producing bacteria have now spread all over the world. Infections caused
by those bacteria are difficult to treat. Therefore, there is an urgent need for accurate and fast …

The global spread of Klebsiella pneumoniae producing Klebsiella pneumoniae
carbapenemase (KPC) has been mainly associated with the dissemination of high-risk …

Klebsiella pneumoniae is a major human pathogen responsible for high morbidity and
mortality rates. The emergence and spread of strains resistant to multiple antimicrobial …

Antimicrobial resistance (AMR) is a global public-health emergency, which threatens the
advances made by modern medical care over the past century. The World Health …