Paleoproteomics

C Warinner, K Korzow Richter, MJ Collins - Chemical reviews, 2022 - ACS Publications
Paleoproteomics, the study of ancient proteins, is a rapidly growing field at the intersection of
molecular biology, paleontology, archaeology, paleoecology, and history. Paleoproteomics …

Evolutionary causes and consequences of bacterial antibiotic persistence

E Bakkeren, M Diard, WD Hardt - Nature Reviews Microbiology, 2020 - nature.com
Antibiotic treatment failure is of growing concern. Genetically encoded resistance is key in
driving this process. However, there is increasing evidence that bacterial antibiotic …

Designer dual therapy nanolayered implant coatings eradicate biofilms and accelerate bone tissue repair

J Min, KY Choi, EC Dreaden, RF Padera, RD Braatz… - ACS …, 2016 - ACS Publications
Infections associated with orthopedic implants cause increased morbidity and significant
healthcare cost. A prolonged and expensive two-stage procedure requiring two surgical …

Engineering Dynamic Defect of CeIII/CeIV‐Based Metal‐Organic Framework through Ultrasound‐Triggered Au Electron Trapper for Sonodynamic Therapy of …

Q Zheng, X Liu, S Gao, Z Cui, S Wu, Y Liang, Z Li… - Small, 2023 - Wiley Online Library
Defect engineering is an important way to tune the catalytic properties of metal‐organic
framework (MOF), yet precise control of defects is difficult to achieve. Herein, a cerium …

The biofilm‐associated bacterial infections unrelated to indwelling devices

R Mirzaei, R Mohammadzadeh, MY Alikhani… - IUBMB …, 2020 - Wiley Online Library
Biofilms are microbial communities established in the self‐produced extracellular
substances that include up to 80% of associated microbial infections. During biofilm …

RNA-dependent regulation of virulence in pathogenic bacteria

S Chakravarty, E Massé - Frontiers in cellular and infection …, 2019 - frontiersin.org
During infection, bacterial pathogens successfully sense, respond and adapt to a myriad of
harsh environments presented by the mammalian host. This exquisite level of adaptation …

Dual-Functionalized Injectable pH-Responsive Hydrogels Loaded with Magnesium Peroxide for the Treatment of Implant-Associated Infection

Z Peng, Y Du, M Song, C Sun, Y Xu… - … Applied Materials & …, 2024 - ACS Publications
Implant-associated infections frequently complicate orthopedic surgeries, resulting in
challenging issues. The current therapy of antibiotic treatment and surgical debridement …

Astragalin mitigates inflammatory osteolysis by negatively modulating osteoclastogenesis via ROS and MAPK signaling pathway

F Xing, L Geng, H Guan, D Liu, Y Li, L Zeng… - International …, 2022 - Elsevier
Inflammatory bone destruction has gradually attracted attention worldwide and has been
observed in several kinds of pathological bone diseases, such as osteoarthritis …

In Situ Gelling Hydrogel with Anti-Bacterial Activity and Bone Healing Property for Treatment of Osteomyelitis

SW Jung, SH Oh, IS Lee, JH Byun, JH Lee - Tissue engineering and …, 2019 - Springer
Background: Despite the development of progressive surgical techniques and antibiotics,
osteomyelitis is a big challenge for orthopedic surgeons. The main aim of this study is to …

Lytic bacteriophages against multidrug-resistant Staphylococcus aureus, Enterococcus faecalis and Escherichia coli isolates from orthopaedic implant-associated …

J Barros, LDR Melo, P Poeta, G Igrejas… - International journal of …, 2019 - Elsevier
Orthopaedic implant-associated infections are a devastating complication of orthopaedic
surgery with a significant impact on patients and healthcare systems. The aims of this work …