Bacterial inclusion bodies: a treasure trove of bioactive proteins
Recombinant proteins expressed as bacterial inclusion bodies (IBs) are now receiving
tremendous attention for many diverse applications in the areas of industrial and medical …
tremendous attention for many diverse applications in the areas of industrial and medical …
Amyloid-like aggregation of bovine serum albumin at physiological temperature induced by cross-seeding effect of HEWL amyloid aggregates
S Nirwal, V Bharathi, BK Patel - Biophysical Chemistry, 2021 - Elsevier
BSA can form amyloid-like aggregates in vitro at 65° C. Heterologous amyloid can
proposedly cross-seed other protein's aggregation, however, general mechanisms and …
proposedly cross-seed other protein's aggregation, however, general mechanisms and …
The role of surface properties on protein aggregation behavior in aqueous solution of different pH values
H Lan, H Liu, Y Ye, Z Yin - AAPS PharmSciTech, 2020 - Springer
This study aimed to investigate the effect of pH-mediated surface properties of bovine serum
albumin (BSA) on protein aggregation and the changes of protein structure and colloidal …
albumin (BSA) on protein aggregation and the changes of protein structure and colloidal …
Solubilization and refolding of inclusion body proteins
Expression of heterologous proteins in E. coli often leads to the formation of protein
aggregates known as inclusion bodies (IBs). Inclusion body aggregates pose a major hurdle …
aggregates known as inclusion bodies (IBs). Inclusion body aggregates pose a major hurdle …
Microwave-assisted one-pot multicomponent synthesis of steroidal pyrido [2, 3-d] pyrimidines and their possible implications in drug development
Protein misfolding can lead to fibrillar and non-fibrillar deposits which are the signs of
countless human diseases. A promising strategy for the prevention of such diseases is the …
countless human diseases. A promising strategy for the prevention of such diseases is the …
Investigating chaperone like activity of green silver nanoparticles: possible implications in drug development
Protein aggregation and amyloidogenesis have been associated with several
neurodegenerative disorders like Alzheimer's, Parkinson's etc. Unfortunately, there are still …
neurodegenerative disorders like Alzheimer's, Parkinson's etc. Unfortunately, there are still …
Inhibition of protein misfolding and aggregation by steroidal quinoxalin-2 (1H)-one and their molecular docking studies
A series of D-ring fused 16-substituted steroidal quinoxalin-2 (1H)-one attached to an
electron-releasing (ER) or electron-withdrawing (EW) groups via steroidal oxoacetate …
electron-releasing (ER) or electron-withdrawing (EW) groups via steroidal oxoacetate …
Green synthesis of silver nanoparticles, its characterization, and chaperone-like activity in the aggregation inhibition of α-chymotrypsinogen A
Consumption of silver nanoparticles (AgNPs) has been increased many folds due to its
antimicrobial actions resulting in its widespread incorporation into a wide range of …
antimicrobial actions resulting in its widespread incorporation into a wide range of …
Molecular crowding induced loss of native conformation and aggregation of α-chymotrypsinogen A
Conformational characterization of the folding and unfolding pathway is the key to studying
protein-macromolecular interactions. Also, we know that unfolding mediated protein …
protein-macromolecular interactions. Also, we know that unfolding mediated protein …