The hematologic system as a marker of organ dysfunction in sepsis

WC Aird - Mayo Clinic Proceedings, 2003 - Elsevier
Sepsis with acute organ dysfunction (severe sepsis) results from a systemic proinflammatory
and procoagulant response to infection. Organ dysfunction in the patient with sepsis is …

Red blood cell physiology in critical illness

M Scharte, MP Fink - Critical care medicine, 2003 - journals.lww.com
Red blood cell physiology in critical illness : Critical Care Medicine Red blood cell physiology
in critical illness : Critical Care Medicine SCCM Pediatric Critical Care Medicine Critical Care …

Anemia and blood transfusion in critically ill patients

JL Vincent, JF Baron, K Reinhart, L Gattinoni, L Thijs… - Jama, 2002 - jamanetwork.com
ContextAnemia is a common problem in critically ill patients admitted to intensive care units
(ICUs), but the consequences of anemia on morbidity and mortality in the critically ill is …

Perioperative anemia: an independent risk factor for infection, mortality, and resource utilization in surgery

JR Dunne, D Malone, JK Tracy, C Gannon… - Journal of Surgical …, 2002 - Elsevier
Background. Previous studies on patients with hip fractures and in patients with colorectal
cancer have documented that perioperative transfusion is associated with a significant …

Nutritional deficiencies and blunted erythropoietin response as causes of the Amemia of critical illness

RM Rodriguez, HL Corwin, A Gettinger, MJ Corwin… - Journal of critical …, 2001 - Elsevier
Purpose The purpose of this article was to determine the prevalence of iron, vitamin B12,
and folate deficiency and to evaluate the erythropoietin (EPO) response to anemia in a …

Efficacy of recombinant human erythropoietin in the critically ill patient: a randomized, double-blind, placebo-controlled trial

HL Corwin, A Gettinger, RM Rodriguez… - Critical care …, 2001 - journals.lww.com
Efficacy of recombinant human erythropoietin in the critical... : Critical Care Medicine Efficacy of
recombinant human erythropoietin in the critically ill patient: A randomized, double-blind …

Anemia in the critically ill

A Shander - Critical care clinics, 2004 - criticalcare.theclinics.com
The US National Center for Health Statistics, a division of the US Department of Health and
Human Services, estimated in 1996 that 3.4 million Americans were living with anemia …

The effects of iron deficiency on lymphocyte cytokine production and activation: preservation of hepatic iron but not at all cost

J Jason, LK Archibald, OC Nwanyanwu… - Clinical & …, 2001 - academic.oup.com
Worldwide, over 40% of children have iron deficiency anaemia, frequently associated with
infections. Certain cytokines are involved in both immune activation/response to infection …

Anemia of the critically ill:“Acute” anemia of chronic disease

HL Corwin, SB Krantz - Critical care medicine, 2000 - journals.lww.com
Anemia is common in the critically ill. By intensive care unit (ICU) day 3,∼ 95% of patients
have hemoglobin concentrations below normal (1). Phlebotomy and gastrointestinal blood …

Safety and efficacy of erythropoiesis-stimulating agents in critically ill patients admitted to the intensive care unit: a systematic review and meta-analysis

E Litton, P Latham, J Inman, J Luo, P Allan - Intensive Care Medicine, 2019 - Springer
Purpose Severe immune dysregulation is common in patients admitted to the intensive care
unit (ICU) and is associated with adverse outcomes. Erythropoietin-stimulating agents …