Drosophila Cellular Immunity Against Parasitoid Wasps: A Complex and Time-Dependent Process

C Kim-Jo, JL Gatti, M Poirié - Frontiers in Physiology, 2019 - frontiersin.org
Host-parasitoid interactions are among the most studied interactions between invertebrates
because of their fundamental interest–the evolution of original traits in parasitoids–and …

Novel organelles with elements of bacterial and eukaryotic secretion systems weaponize parasites of Drosophila

ME Heavner, J Ramroop, G Gueguen, G Ramrattan… - Current Biology, 2017 - cell.com
The evolutionary success of parasitoid wasps, a highly diverse group of insects widely used
in biocontrol, depends on a variety of life history strategies in conflict with those of their hosts …

Immune Suppressive Extracellular Vesicle Proteins of Leptopilina heterotoma Are Encoded in the Wasp Genome

B Wey, ME Heavner, KT Wittmeyer… - G3: Genes …, 2020 - academic.oup.com
Leptopilina heterotoma are obligate parasitoid wasps that develop in the body of their
Drosophila hosts. During oviposition, female wasps introduce venom into the larval hosts' …

A parasitoid wasp of Drosophila employs preemptive and reactive strategies to deplete its host's blood cells

JR Ramroop, ME Heavner, ZH Razzak… - PLoS …, 2021 - journals.plos.org
The wasps Leptopilina heterotoma parasitize and ingest their Drosophila hosts. They
produce extracellular vesicles (EVs) in the venom that are packed with proteins, some of …

A Novel Method for Primary Blood Cell Culturing and Selection in Drosophila melanogaster

E Kúthy-Sutus, B Kharrat, E Gábor, G Csordás, R Sinka… - Cells, 2022 - mdpi.com
The blood cells of the fruit fly Drosophila melanogaster show many similarities to their
vertebrate counterparts, both in their functions and their differentiation. In the past decades …

In Silico Analysis of a Drosophila Parasitoid Venom Peptide Reveals Prevalence of the Cation–Polar–Cation Clip Motif in Knottin Proteins

J Arguelles, J Lee, LV Cardenas, S Govind, S Singh - Pathogens, 2023 - mdpi.com
As generalist parasitoid wasps, Leptopilina heterotoma are highly successful on many
species of fruit flies of the genus Drosophila. The parasitoids produce specialized multi …