Current prospects of nutraceuticals: A review

V Sachdeva, A Roy… - Current pharmaceutical …, 2020 - ingentaconnect.com
Nutraceuticals are dietary supplements, utilized to ameliorate health, delay senescence,
prevent diseases, and support the proper functioning of the human body. Currently …

Emodin-A natural anthraquinone derivative with diverse pharmacological activities

RB Semwal, DK Semwal, S Combrinck, A Viljoen - Phytochemistry, 2021 - Elsevier
Abstract Emodin (1, 3, 8-trihydroxy-6-methyl-anthraquinone) is a natural anthraquinone
derivative that is present in numerous globally renowned herbal medicines. It is recognised …

[HTML][HTML] Exploring the journey of emodin as a potential neuroprotective agent: novel therapeutic insights with molecular mechanism of action

S Mitra, J Anjum, M Muni, R Das, A Rauf, F Islam… - Biomedicine & …, 2022 - Elsevier
Emodin is an anthraquinone derivative found in the roots and bark of a variety of plants,
molds, and lichens. Emodin has been used as a traditional medication for more than 2000 …

Formation and biological targets of quinones: cytotoxic versus cytoprotective effects

JL Bolton, T Dunlap - Chemical research in toxicology, 2017 - ACS Publications
Quinones represent a class of toxicological intermediates, which can create a variety of
hazardous effects in vivo including, acute cytotoxicity, immunotoxicity, and carcinogenesis …

ATP citrate lyase (ACLY) inhibitors: An anti-cancer strategy at the crossroads of glucose and lipid metabolism

C Granchi - European journal of medicinal chemistry, 2018 - Elsevier
ATP citrate lyase (ACLY) is a cytosolic homotetrameric enzyme that catalyzes the conversion
of citrate and coenzyme A (CoA) to acetyl-CoA and oxaloacetate, with the simultaneous …

[HTML][HTML] De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae

M Li, KR Kildegaard, Y Chen, A Rodriguez… - Metabolic …, 2015 - Elsevier
Resveratrol is a natural antioxidant compound, used as food supplement and cosmetic
ingredient. Microbial production of resveratrol has until now been achieved by …

Is emodin with anticancer effects completely innocent? Two sides of the coin

EK Akkol, II Tatlı, GŞ Karatoprak, OT Ağar, Ç Yücel… - Cancers, 2021 - mdpi.com
Simple Summary For cancer treatment, which is one of the most common and serious
diseases of our day, miraculous secondary compounds of natural resources, which cannot …

[HTML][HTML] Emodin reduces breast cancer lung metastasis by suppressing macrophage-induced breast cancer cell epithelial-mesenchymal transition and cancer stem …

Q Liu, J Hodge, J Wang, Y Wang, L Wang, UP Singh… - Theranostics, 2020 - ncbi.nlm.nih.gov
Our previous studies demonstrated that the natural compound emodin blocks the tumor-
promoting feedforward interactions between cancer cells and macrophages, and thus …

Anti-cancer natural products isolated from chinese medicinal herbs

W Tan, J Lu, M Huang, Y Li, M Chen, G Wu, J Gong… - Chinese medicine, 2011 - Springer
In recent years, a number of natural products isolated from Chinese herbs have been found
to inhibit proliferation, induce apoptosis, suppress angiogenesis, retard metastasis and …

First-pass metabolism via UDP-glucuronosyltransferase: a barrier to oral bioavailability of phenolics

B Wu, K Kulkarni, S Basu, S Zhang, M Hu - Journal of pharmaceutical …, 2011 - Elsevier
Glucuronidation mediated by UDP-glucuronosyltransferases (UGTs) is a significant
metabolic pathway that facilitates efficient elimination of numerous endobiotics and …