Type 2 diabetes and osteoporosis: a guide to optimal management

SΑ Paschou, AD Dede, PG Anagnostis… - The Journal of …, 2017 - academic.oup.com
Context Both type 2 diabetes (T2D) and osteoporosis are affected by aging and quite often
coexist. Furthermore, the fracture risk in patients with T2D is increased. The aim of this article …

Assessment and treatment of osteoporosis and fractures in type 2 diabetes

A Sheu, JR Greenfield, CP White, JR Center - Trends in Endocrinology & …, 2022 - cell.com
There is substantial, and growing, evidence that type 2 diabetes (T2D) is associated with
skeletal fragility, despite often preserved bone mineral density. As post-fracture outcomes …

Treatment of diabetes in older adults: an Endocrine Society clinical practice guideline

D LeRoith, GJ Biessels, SS Braithwaite… - The Journal of …, 2019 - academic.oup.com
Objective The objective is to formulate clinical practice guidelines for the treatment of
diabetes in older adults. Conclusions Diabetes, particularly type 2, is becoming more …

An update on therapies for the treatment of diabetes-induced osteoporosis

S Mohsin, MMYH Baniyas… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Currently, 424 million people aged between 20 and 79 years worldwide are
diabetic. More than 25% of adults aged over 65 years in North America have Type 2 …

Diabetes pharmacotherapy and effects on the musculoskeletal system

E Kalaitzoglou, JL Fowlkes, I Popescu… - … research and reviews, 2019 - Wiley Online Library
Persons with type 1 or type 2 diabetes have a significantly higher fracture risk than age‐
matched persons without diabetes, attributed to disease‐specific deficits in the …

Diabetes mellitus-induced bone fragility

I Kanazawa, T Sugimoto - Internal medicine, 2018 - jstage.jst.go.jp
Accumulating evidence has shown that the risk of osteoporotic fractures is increased in
patients with diabetes mellitus (DM). Thus, DM-induced bone fragility has been recently …

The use of metformin, insulin, sulphonylureas, and thiazolidinediones and the risk of fracture: Systematic review and meta‐analysis of observational studies

K Hidayat, X Du, MJ Wu, BM Shi - Obesity Reviews, 2019 - Wiley Online Library
Certain glucose‐lowering medications have been implicated in the risk of fracture. While
there is convincing evidence from randomized controlled trials (RCTs) that thiazolidinedione …

[HTML][HTML] Challenges to improve bone healing under diabetic conditions

Y Chen, Y Zhou, J Lin, S Zhang - Frontiers in endocrinology, 2022 - frontiersin.org
Diabetes mellitus (DM) can affect bone metabolism and the bone microenvironment,
resulting in impaired bone healing. The mechanisms include oxidative stress, inflammation …

Glycemic control and insulin treatment alter fracture risk in older men with type 2 diabetes mellitus

RH Lee, R Sloane, C Pieper, KW Lyles… - Journal of Bone and …, 2019 - academic.oup.com
Diabetes mellitus among older men has been associated with increased bone mineral
density but paradoxically increased fracture risk. Given the interactions among medication …

[HTML][HTML] Type 2 diabetes mellitus and vertebral fracture risk

F Koromani, S Ghatan, M van Hoek… - Current Osteoporosis …, 2021 - Springer
Abstract Purpose of Review The purpose of this review is to summarize the recently
published evidence concerning vertebral fracture risk in individuals with diabetes mellitus …