Protein interaction networks: centrality, modularity, dynamics, and applications

X Meng, W Li, X Peng, Y Li, M Li - Frontiers of Computer Science, 2021 - Springer
In the post-genomic era, proteomics has achieved significant theoretical and practical
advances with the development of high-throughput technologies. Especially the rapid …

PPI‐Detect: a support vector machine model for sequence‐based prediction of protein–protein interactions

S Romero‐Molina, YB Ruiz‐Blanco… - Journal of …, 2019 - Wiley Online Library
The prediction of peptide–protein or protein–protein interactions (PPI) is a challenging task,
especially if amino acid sequences are the only information available. Machine learning …

[HTML][HTML] Unveiling network-based functional features through integration of gene expression into protein networks

M Jalili, T Gebhardt, O Wolkenhauer… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Decoding health and disease phenotypes is one of the fundamental objectives in
biomedicine. Whereas high-throughput omics approaches are available, it is evident that …

Moth–flame optimization-based algorithm with synthetic dynamic PPI networks for discovering protein complexes

X Lei, M Fang, H Fujita - Knowledge-Based Systems, 2019 - Elsevier
The prediction of protein complex in protein–protein interaction (PPI) networks plays such a
crucial role in the understanding of biological processes. This paper presents a moth–flame …

Identification of protein complexes by using a spatial and temporal active protein interaction network

M Li, X Meng, R Zheng, FX Wu, Y Li… - … /ACM transactions on …, 2017 - ieeexplore.ieee.org
The rapid development of proteomics and high-throughput technologies has produced a
large amount of Protein-Protein Interaction (PPI) data, which makes it possible for …

Identifying protein complexes based on an edge weight algorithm and core-attachment structure

R Wang, G Liu, C Wang - BMC bioinformatics, 2019 - Springer
Background Protein complex identification from protein-protein interaction (PPI) networks is
crucial for understanding cellular organization principles and functional mechanisms. In …

A multi-network clustering method for detecting protein complexes from multiple heterogeneous networks

L Ou-Yang, H Yan, XF Zhang - BMC bioinformatics, 2017 - Springer
Background The accurate identification of protein complexes is important for the
understanding of cellular organization. Up to now, computational methods for protein …

Temporal Graph Generation Featuring Time-Bound Communities

S Zheng, C Wang, C Wu, Y Lou… - 2024 IEEE 40th …, 2024 - ieeexplore.ieee.org
Synthetic graph datasets are crucial for the assessment of network analysis algorithms,
providing a measure of their effectiveness and efficiency. However, most existing generation …

DPCT: a dynamic method for detecting protein complexes from TAP-aware weighted PPI network

A SabziNezhad, S Jalili - Frontiers in genetics, 2020 - frontiersin.org
Detecting protein complexes from the Protein-Protein interaction network (PPI) is the
essence of discovering the rules of the cellular world. There is a large amount of PPI data …

Reconstruction of dynamic protein–protein interaction network via graph convolutional network

Y He, F Zhu - Expert Systems with Applications, 2025 - Elsevier
Traditional researches predominantly rely on static protein network models, which present
highly averaged and idealized representations of protein networks. However, these models …