Molecular mechanisms during hepatitis B infection and the effects of the virus variability

M Campos-Valdez, HC Monroy-Ramírez… - Viruses, 2021 - mdpi.com
The immunopathogenesis and molecular mechanisms involved during a hepatitis B virus
(HBV) infection have made the approaches for research complex, especially concerning the …

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

SZ Bahojb Mahdavi, A Jebelli… - Medicinal Research …, 2024 - Wiley Online Library
Infections caused by viruses as the smallest infectious agents, pose a major threat to global
public health. Viral infections utilize different host mechanisms to facilitate their own …

Efficacy and safety of bulevirtide plus tenofovir disoproxil fumarate in real-world patients with chronic hepatitis B and D co-infection

T Herta, M Hahn, M Maier, J Fischer, J Niemeyer… - Pathogens, 2022 - mdpi.com
Background: The hepatitis B and D virus (HBV/HDV) hepatocyte entry inhibitor bulevirtide
(BLV) has been available in Europe since July 2020, after the registrational trial MYR202 …

Ergosterol peroxide inhibits HBV infection by inhibiting the binding of the pre-S1 domain of LHBsAg to NTCP

H Huang, HC Huang, WC Chiou, LC Lin, JC Chen… - Antiviral Research, 2021 - Elsevier
Hepatitis B virus (HBV) infection leads to severe liver diseases, including cirrhosis and
hepatocellular carcinoma (HCC). More than 257 million individuals are chronically infected …

Genotyping Hepatitis B virus by Next-Generation Sequencing: Detection of Mixed Infections and Analysis of Sequence Conservation

E Dopico, M Vila, D Tabernero, J Gregori… - International Journal of …, 2024 - mdpi.com
Our aim was to develop an accurate, highly sensitive method for HBV genotype
determination and detection of genotype mixtures. We examined the preS and 5′ end of …

Sophisticated viral quasispecies with a genotype-related pattern of mutations in the hepatitis BX gene of HBeAg-ve chronically infected patients

MF Cortese, C González, J Gregori, R Casillas… - Scientific reports, 2021 - nature.com
Patients with HBeAg-negative chronic infection (CI) have not been extensively studied
because of low viremia. The HBx protein, encoded by HBX, has a key role in viral …

Diverse effects of the NTCP p. Ser267Phe variant on disease progression during chronic HBV infection and on HBV preS1 variability

F Yang, L Wu, W Xu, Y Liu, L Zhen, G Ning… - Frontiers in Cellular …, 2019 - frontiersin.org
The sodium taurocholate co-transporting polypeptide (NTCP) acts as a cellular receptor for
the hepatitis B virus (HBV) infection on host hepatocytes. We aim to investigate how the …

[PDF][PDF] Efficacy and Safety of Bulevirtide plus Tenofovir Disoproxil Fumarate in Real-World Patients with Chronic Hepatitis B and D Co-Infection. Pathogens 2022, 11 …

T Herta, M Hahn, M Maier, J Fischer, J Niemeyer… - 2022 - pdfs.semanticscholar.org
Background: The hepatitis B and D virus (HBV/HDV) hepatocyte entry inhibitor bulevirtide
(BLV) has been available in Europe since July 2020, after the registrational trial MYR202 …

NTCP gene polymorphisms and hepatitis B virus infection status in a Ghanaian population

E Nyarko, C Obirikorang, W Owiredu, EA Adu… - Virology journal, 2020 - Springer
Background SLC10A1 gene codes NTCP, a receptor through which the hepatitis B virus
(HBV) gets access into hepatocytes-a stage of the viral cycle necessary for replication …

Significance of hydrophobic and charged sequence similarities in sodium-bile acid cotransporter and vitamin D-binding protein macrophage activating factor

IR Zunaid, S Pacini, M Ruggiero - bioRxiv, 2020 - biorxiv.org
Sodium-bile acid cotransporter, also denominated sodium-taurocholate cotransporting
polypeptide (NTCP) is an integral membrane protein with multiple hydrophobic …