Objective: In this study, available medical literature were reviewed to determine whether
brain hypoxia as measured by brain tissue oxygen (Bto 2) levels is associated with …

Abstract AS OUTCOMES HAVE improved for patients with aneurysmal subarachnoid
hemorrhage, most mortality and morbidity that occur today are the result of severe diffuse …

Objectives: A relationship between reduced brain tissue oxygenation and poor outcome
following severe traumatic brain injury has been reported in observational studies. We …

Objectives: We have sought to develop an automated methodology for the continuous
updating of optimal cerebral perfusion pressure (CPP opt) for patients after severe traumatic …

There is a substantial body of evidence that systemic hypotension independently increases
the morbidity and mortality from TBI, both clinical10, 14, 24, 26 and histological. 15, 29 CPP …

Object. An intracranial pressure (ICP) monitor, from which cerebral perfusion pressure (CPP)
is estimated, is recommended in the care of severe traumatic brain injury (TBI) …

Object The object of this study was to determine whether brain tissue oxygen (PbtO 2)–
based therapy or intracranial pressure (ICP)/cerebral perfusion pressure (CPP)–based …

Object Cerebral ischemia is the leading cause of preventable death in cases of major
trauma with severe traumatic brain injury (TBI). Intracranial pressure (ICP) control and …

Objective: Hypertensive, hypervolemic, hemodilution therapy (triple-H therapy) is a generally
accepted treatment for cerebral vasospasm after subarachnoid hemorrhage. However, the …

Objective: In this study we have used 15 O positron emission tomography, brain tissue
oxygen monitoring, and cerebral microdialysis to assess the effects of cerebral perfusion …