Ossification is a tightly regulated process, performed by specialized cells called osteoblasts.
Dysregulation of this process may cause inadequate or excessive mineralization of bones or …

The initiation of osteogenesis primarily occurs as mesenchymal stem cells undergo
differentiation into osteoblasts. This differentiation process plays a crucial role in bone …

Abstract Machine learning algorithms can be trained to estimate age from brain structural
MRI. The difference between an individual's predicted and chronological age, predicted age …

Osteoarthritis (OA) is a degenerative joint disease that involves the destruction of articular
cartilage and eventually leads to disability. Molecules that promote the selective …

INTRODUCTION: Biodentine (Septodont, Saint Maur des Faussés, France), a new tricalcium
silicate-based cement, has recently been commercialized and advertised as a bioactive …

BACKGROUND: Osteoarthritis is the most common form of arthritis worldwide and is a major
cause of pain and disability in elderly people. The health economic burden of osteoarthritis …

TGF-β1 is a ubiquitous growth factor that is implicated in the control of proliferation,
migration, differentiation, and survival of many different cell types. It influences such diverse …

Emerging evidence indicates that microRNAs (miRNAs) play essential roles in regulating
osteoblastogenesis and bone formation. However, the role of miRNA in osteoblast …

Osteogenesis is the process of new bone formation where transcription factors play an
important role in controlling cell proliferation and differentiation. Runt-related transcription …

Biological systems involving short-range activators and long-range inhibitors can generate
complex patterns. Reaction-diffusion models postulate that differences in signaling range …