Periodontal disease is an inflammatory disease caused by periodontopathogenic bacteria,
which eventually leads to bone tissue (alveolar bone) destruction as inflammation persists …

Periodontitis, a bacterium-induced inflammatory disease that is characterized by alveolar
bone loss, is highly prevalent worldwide. Elucidating the underlying mechanisms of alveolar …

Osteoclasts are large multinucleated cells from hematopoietic origin and are responsible for
bone resorption. A balance between osteoclastic bone resorption and osteoblastic bone …

Bone has the capacity to alter its mass and structure to its mechanical environment.
Osteocytes are the predominant bone cells and it is generally accepted that the osteocytes …

Internal inflammatory root resorption is a relatively rare resorption that begins in the root
canal and destroys surrounding dental hard tissues. Odontoclastic multinuclear cells are …

Periodontitis is an inflammatory disease characterized by periodontal pocket formation and
alveolar bone resorption. Periodontal bone resorption is induced by osteoclasts and …

During the last decade it has become clear that periodontal ligament fibroblasts may
contribute to the in vitro differentiation of osteoclasts. We surveyed the current findings …

Accumulated lines of evidence suggest that hyperimmune responses to periodontal bacteria
result in the destruction of periodontal connective tissue and alveolar bone. The etiological …

Scheres N, Laine ML, de Vries TJ, Everts V, van Winkelhoff AJ. Gingival and periodontal
ligament fibroblasts differ in their inflammatory response to viable Porphyromonas gingivalis …

Disequilibrium between bone‐forming osteoblasts and bone‐resorbing osteoclasts is
central to many bone diseases. Here, we show that dysregulated expression of …