On virus growth and form

R Zandi, B Dragnea, A Travesset, R Podgornik - Physics Reports, 2020 - Elsevier
We review approaches aimed at deciphering the physical mechanisms responsible for viral
structure and assembly. We discuss the basic principles of condensed matter physics …

Energies and pressures in viruses: contribution of nonspecific electrostatic interactions

A Šiber, AL Božič, R Podgornik - Physical chemistry chemical physics, 2012 - pubs.rsc.org
We summarize some aspects of electrostatic interactions in the context of viruses. A
simplified but, within well defined limitations, reliable approach is used to derive expressions …

[HTML][HTML] Spike proteins of SARS-CoV and SARS-CoV-2 utilize different mechanisms to bind with human ACE2

Y Xie, CB Karki, D Du, H Li, J Wang… - Frontiers in molecular …, 2020 - frontiersin.org
The ongoing outbreak of COVID-19 has been a serious threat to human health worldwide.
The virus SARS-CoV-2 initiates its infection to the human body via the interaction of its spike …

Complexation and coacervation of like-charged polyelectrolytes inspired by mussels

S Kim, J Huang, Y Lee, S Dutta… - Proceedings of the …, 2016 - National Acad Sciences
It is well known that polyelectrolyte complexes and coacervates can form on mixing
oppositely charged polyelectrolytes in aqueous solutions, due to mainly electrostatic …

Electrostatic interactions in biological DNA-related systems

AG Cherstvy - Physical Chemistry Chemical Physics, 2011 - pubs.rsc.org
In this perspective article, we focus on recent developments in the theory of charge effects in
biological DNA-related systems. The electrostatic effects on different levels of DNA …

Phase diagram of self-assembled viral capsid protein polymorphs

L Lavelle, M Gingery, M Phillips… - The Journal of …, 2009 - ACS Publications
We present an experimental study of the self-assembly of capsid proteins of the cowpea
chlorotic mosaic virus (CCMV), in the absence of the viral genome, as a function of pH and …

Transient oligomerization of the SARS-CoV N protein–implication for virus ribonucleoprotein packaging

C Chang, CMM Chen, M Chiang, Y Hsu, T Huang - PloS one, 2013 - journals.plos.org
The nucleocapsid (N) phosphoprotein of the severe acute respiratory syndrome coronavirus
(SARS-CoV) packages the viral genome into a helical ribonucleocapsid and plays a …

Pathways for virus assembly around nucleic acids

JD Perlmutter, MR Perkett, MF Hagan - Journal of molecular biology, 2014 - Elsevier
Understanding the pathways by which viral capsid proteins assemble around their genomes
could identify key intermediates as potential drug targets. In this work, we use computer …

Nonsymmetrical dynamics of the HBV capsid assembly and disassembly evidenced by their transient species

M Chevreuil, L Lecoq, S Wang… - The Journal of …, 2020 - ACS Publications
As with many protein multimers studied in biophysics, the assembly and disassembly
dynamical pathways of hepatitis B virus (HBV) capsid proteins are not symmetrical. Using …

All-atom molecular dynamics calculation study of entire poliovirus empty capsids in solution

Y Andoh, N Yoshii, A Yamada, K Fujimoto… - The Journal of …, 2014 - pubs.aip.org
Small viruses that belong, for example, to the Picornaviridae, such as poliovirus and foot-
and-mouth disease virus, consist simply of capsid proteins and a single-stranded RNA …