The serotonin system in autism spectrum disorder: From biomarker to animal models

CL Muller, AMJ Anacker, J Veenstra-VanderWeele - Neuroscience, 2016 - Elsevier
Elevated whole blood serotonin, or hyperserotonemia, was the first biomarker identified in
autism spectrum disorder (ASD) and is present in more than 25% of affected children. The …

Neural circuits for social cognition: implications for autism

M Fernández, I Mollinedo-Gajate, O Peñagarikano - Neuroscience, 2018 - Elsevier
Social neuroscience, the study of the neurobiological basis of social behavior, has become
a major area of current research in behavioral neuroscience and psychiatry, since many …

Switching brain serotonin with oxytocin

R Mottolese, J Redouté, N Costes… - Proceedings of the …, 2014 - National Acad Sciences
Serotonin (5-HT) and oxytocin (OXT) are two neuromodulators involved in human affect and
sociality and in disorders like depression and autism. We asked whether these chemical …

Making room for oxytocin in understanding depression

RJ McQuaid, OA McInnis, A Abizaid… - … & Biobehavioral Reviews, 2014 - Elsevier
Depression is accompanied by an array of neurobiological variations, including altered HPA
axis activity, monoamine, growth factor and inflammatory immune functioning. In addition, a …

[HTML][HTML] Individual differences underlying susceptibility to addiction: Role for the endogenous oxytocin system

FTA Buisman-Pijlman, NM Sumracki, JJ Gordon… - Pharmacology …, 2014 - Elsevier
Recent research shows that the effects of oxytocin are more diverse than initially thought
and that in some cases oxytocin can directly influence the response to drugs and alcohol …

Oxytocin׳ s role in anxiety: A critical appraisal

K MacDonald, D Feifel - Brain research, 2014 - Elsevier
A growing literature suggests that the oxytocin (OT) system may play a role in human anxiety
states, anxiety-related traits, and moreover, that this system may be a target for the …

Oxytocin and estrogen receptor β in the brain: an overview

A Acevedo-Rodriguez, SK Mani… - Frontiers in …, 2015 - frontiersin.org
Oxytocin (OT) is a neuropeptide synthesized primarily by neurons of the paraventricular and
supraoptic nuclei of the hypothalamus. These neurons have axons that project into the …

The social brain: neurobiological basis of affiliative behaviours and psychological well-being

SC Walker, FP McGlone - Neuropeptides, 2013 - Elsevier
The social brain hypothesis proposes that the demands of the social environment provided
the evolutionary pressure that led to the expansion of the primate brain. Consistent with this …

The oxytocin system and early‐life experience‐dependent plastic changes

T Onaka, Y Takayanagi - Journal of Neuroendocrinology, 2021 - Wiley Online Library
Early‐life experience influences social and emotional behaviour in adulthood. Affiliative
tactile stimuli in early life facilitate the development of social and emotional behaviour …

Increasing oxytocin receptor expression in the nucleus accumbens of pre-pubertal female prairie voles enhances alloparental responsiveness and partner preference …

AC Keebaugh, LJ Young - Hormones and behavior, 2011 - Elsevier
Oxytocin receptors (OXTR) in the nucleus accumbens (NAcc) promote alloparental behavior
and partner preference formation in female prairie voles. Within the NAcc there is significant …