Therapeutic Potential of Natural Products in the Treatment of Schistosomiasis
CM Azevedo, CS Meira, JW da Silva, DMN Moura… - Molecules, 2023 - mdpi.com
It is estimated that 250 million people worldwide are affected by schistosomiasis. Disease
transmission is related to the poor sanitation and hygiene habits that affect residents of …
transmission is related to the poor sanitation and hygiene habits that affect residents of …
Brazilian red propolis exhibits antiparasitic properties in vitro and reduces worm burden and egg production in an mouse model harboring either early or chronic …
MP Silva, TM Silva, AC Mengarda, MC Salvadori… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Propolis has been used in folk medicine for thousands of
years and, in the past few decades, it has attracted renewed interest. Although propolis has …
years and, in the past few decades, it has attracted renewed interest. Although propolis has …
Chemotherapy for human schistosomiasis: how far have we come? What's new? Where do we go from here?
Globally, schistosomiasis threatens more than 700 million lives, mostly children, in poor
localities of tropical and sub-tropical areas with morbidity due to acute and chronic …
localities of tropical and sub-tropical areas with morbidity due to acute and chronic …
The idiosyncratic efficacy of spironolactone-loaded PLGA nanoparticles against murine intestinal schistosomiasis
Background Schistosomiasis is a chronic debilitating parasitic disease accompanied with
severe mortality rates. Although praziquantel (PZQ) acts as the sole drug for the …
severe mortality rates. Although praziquantel (PZQ) acts as the sole drug for the …
Licarin A, a neolignan isolated from Nectandra oppositifolia Nees & Mart. (Lauraceae), exhibited moderate preclinical efficacy against Schistosoma mansoni …
AC Mengarda, MP Silva, ME Cirino… - Phytotherapy …, 2021 - Wiley Online Library
Schistosomiasis is a widespread human parasitic disease currently affecting over 200
million people, particularly in poor communities. Chemotherapy for schistosomiasis relies …
million people, particularly in poor communities. Chemotherapy for schistosomiasis relies …
Phenotypic screening of nonsteroidal anti-inflammatory drugs identified mefenamic acid as a drug for the treatment of schistosomiasis
Background Treatment and control of schistosomiasis, one of the most insidious and serious
parasitic diseases, depend almost entirely on a single drug, praziquantel. Since the funding …
parasitic diseases, depend almost entirely on a single drug, praziquantel. Since the funding …
Promethazine Exhibits Antiparasitic Properties In Vitro and Reduces Worm Burden, Egg Production, Hepatomegaly, and Splenomegaly in a Schistosomiasis Animal …
DB Roquini, RM Cogo, AC Mengarda… - Antimicrobial agents …, 2019 - Am Soc Microbiol
The treatment and control of schistosomiasis, a neglected disease that affects more than 200
million people worldwide, rely on the use of a single drug, praziquantel. A vaccine has yet to …
million people worldwide, rely on the use of a single drug, praziquantel. A vaccine has yet to …
Neolignans isolated from Saururus cernuus L. (Saururaceae) exhibit efficacy against Schistosoma mansoni
JR Brito, P Wilairatana, DB Roquini, BC Parra… - Scientific Reports, 2022 - nature.com
Schistosomiasis, a parasitic disease caused by the blood fluke of the genus Schistosoma,
affects over 230 million people, especially in developing countries. Despite the significant …
affects over 230 million people, especially in developing countries. Despite the significant …
Antiparasitic Properties of Cardiovascular Agents against Human Intravascular Parasite Schistosoma mansoni
R Porto, AC Mengarda, RA Cajas, MC Salvadori… - Pharmaceuticals, 2021 - mdpi.com
The intravascular parasitic worm Schistosoma mansoni is a causative agent of
schistosomiasis, a disease of great global public health significance. Praziquantel is the only …
schistosomiasis, a disease of great global public health significance. Praziquantel is the only …
H1-antihistamines as antischistosomal drugs: in vitro and in vivo studies
RP Xavier, AC Mengarda, MP Silva, DB Roquini… - Parasites & …, 2020 - Springer
Background Schistosomiasis is a socioeconomically devastating parasitic infection afflicting
hundreds of millions of people and animals worldwide. It is the most important helminth …
hundreds of millions of people and animals worldwide. It is the most important helminth …