Metabolic homeostasis in fungal infections from the perspective of pathogens, immune cells, and whole-body systems
H Weerasinghe, H Stölting, AJ Rose… - … and Molecular Biology …, 2024 - journals.asm.org
The ability to overcome metabolic stress is a major determinant of outcomes during
infections. Pathogens face nutrient and oxygen deprivation in host niches and during their …
infections. Pathogens face nutrient and oxygen deprivation in host niches and during their …
With age comes resilience: how mitochondrial modulation drives age-associated fluconazole tolerance in Cryptococcus neoformans
K Yoo, S Bhattacharya, NK Oliveira, N Pereira de Sa… - mBio, 2024 - journals.asm.org
Cryptococcus neoformans (Cn) is an opportunistic fungal microorganism that causes life-
threatening meningoencephalitis. During the infection, the microbial population is …
threatening meningoencephalitis. During the infection, the microbial population is …
Deciphering antifungal and antibiofilm mechanisms of isobavachalcone against Cryptococcus neoformans through RNA-seq and functional analyses
W Qian, J Lu, C Gao, Q Liu, Y Li, Q Zeng, J Zhang… - Microbial Cell …, 2024 - Springer
Cryptococcus neoformans has been designated as critical fungal pathogens by the World
Health Organization, mainly due to limited treatment options and the prevalence of …
Health Organization, mainly due to limited treatment options and the prevalence of …
Proteome signatures reveal homeostatic and adaptive oxidative responses by a putative co-chaperone, Wos2, to influence fungal virulence determinants in …
B Ball, A Sukumaran, S Pladwig, S Kazi… - Microbiology …, 2024 - journals.asm.org
The increasing prevalence of invasive fungal pathogens is dramatically changing the clinical
landscape of infectious diseases, posing an imminent threat to public health. Specifically …
landscape of infectious diseases, posing an imminent threat to public health. Specifically …
Measuring Stress Phenotypes in Cryptococcus neoformans
R Upadhya, C Probst, JA Alspaugh… - … neoformans: Methods and …, 2024 - Springer
Cryptococcus neoformans is an opportunistic human fungal pathogen capable of surviving
in a wide range of environments and hosts. It has been developed as a model organism to …
in a wide range of environments and hosts. It has been developed as a model organism to …
Achieving Resilience in Aging: How Mitochondrial Modulation Drives Age-associated Fluconazole Tolerance in Cryptococcus neoformans
K Yoo, NK Oliveira, S Bhattacharya, BC Fries - bioRxiv, 2024 - biorxiv.org
Cryptococcus neoformans (Cn) is an opportunistic fungal microorganism that causes life-
threatening meningoencephalitis. During the infection, the microbial population is …
threatening meningoencephalitis. During the infection, the microbial population is …
Discovery and characterization of new strategies to combat Cryptococcus neoformans
B Ball - 2024 - atrium.lib.uoguelph.ca
Combatting the increasing rate of fungal infections is a top priority to protect global health.
Cryptococcus neoformans is an opportunistic fungal pathogen equipped with sophisticated …
Cryptococcus neoformans is an opportunistic fungal pathogen equipped with sophisticated …