Methionine aminopeptidases: Potential therapeutic target for microsporidia and other microbes
BC Das, P Chokkalingam, MA Shareef… - Journal of Eukaryotic …, 2024 - Wiley Online Library
Methionine aminopeptidases (MetAPs) have emerged as a target for medicinal chemists in
the quest for novel therapeutic agents for treating cancer, obesity, and other disorders …
the quest for novel therapeutic agents for treating cancer, obesity, and other disorders …
Novel Antibacterial Targets in Protein Biogenesis Pathways
Antibiotic resistance has emerged as a global threat due to the ability of bacteria to quickly
evolve in response to the selection pressure induced by anti‐infective drugs. Thus, there is …
evolve in response to the selection pressure induced by anti‐infective drugs. Thus, there is …
In silico study of novel marine alkaloid jolynamine and other marine compounds via molecular docking, MM-GBSA binding energy prediction, ADMET evaluation, and …
In this research article bacterial (Escherichia coli and Pseudomonas aeruginosa) and fungal
(Aspergillus niger and Candida albicans) enzymes are used for molecular docking of novel …
(Aspergillus niger and Candida albicans) enzymes are used for molecular docking of novel …
Synthesis and Antibacterial Evaluation of 3,4‐Dihydro‐1H‐benzo[b]azepine‐2,5‐dione Derivatives
Fused‐azepinones are interesting heterocyclic scaffolds present in various natural products
and synthetic derivatives with potent kinase inhibition, anti‐cancer, anti‐inflammatory, anti …
and synthetic derivatives with potent kinase inhibition, anti‐cancer, anti‐inflammatory, anti …
In Silico Design and in Vitro Assessment of Bicyclic Trifluoromethylated Pyrroles as New Antibacterial and Antifungal Agents
QSAR studies on the number of compounds tested as S. aureus inhibitors were performed
using an interactive Online Chemical Database and Modeling Environment (OCHEM) web …
using an interactive Online Chemical Database and Modeling Environment (OCHEM) web …
The identification of inhibitory compounds of Rickettsia prowazekii methionine aminopeptidase for antibacterial applications
TR Helgren, ES Seven, C Chen, TE Edwards… - Bioorganic & medicinal …, 2018 - Elsevier
Methionine aminopeptidase (MetAP) is a dinuclear metalloprotease responsible for the
cleavage of methionine initiator residues from nascent proteins. MetAP activity is necessary …
cleavage of methionine initiator residues from nascent proteins. MetAP activity is necessary …
Methionine aminopeptidases
Methionine aminopeptidases (MetAPs) have been investigated for decades, and
pharmacological inhibition of MetAPs has been pursued to treat diseases such as viral …
pharmacological inhibition of MetAPs has been pursued to treat diseases such as viral …
Synthesis, development and biological evaluation of new antimicrobial compounds
VSK Pallabothula - 2024 - dspace.cuni.cz
This doctoral dissertation is a collection of published works with commentary along with
various contributions throughout the doctoral study program. In our research work, we …
various contributions throughout the doctoral study program. In our research work, we …
[PDF][PDF] Molecular Docking Studies of Novel Furan-azetidinone Hybrids as Potential Inhibitors of Escherichia coli
J Jays, S Mohan, J Saravanan - Indian J. Pharm. Educ. Res., 2019 - ijper.org
Escherichia coli is the predominant gram negative bacteria responsible for a variety of
hospital-acquired infections and urinary tract infections. As the bacterial strains are rapidly …
hospital-acquired infections and urinary tract infections. As the bacterial strains are rapidly …
Grundlegende Untersuchungen zur Entwicklung Bioorthogonaler Reaktionssysteme auf Basis von Olefinmetathesereaktionen
T Benkert - 2024 - search.proquest.com
Die vorliegende Arbeit untersuchte verschiedene Wege zur Herstellung einer BRS mit einer
RCM als abschließender, entscheidender Reaktion, basierend auf vielversprechenden …
RCM als abschließender, entscheidender Reaktion, basierend auf vielversprechenden …