Mechanisms of action of ionic liquids on living cells: The state of the art

P Kumari, VVS Pillai, A Benedetto - Biophysical reviews, 2020 - Springer
Ionic liquids (ILs) are a relatively new class of organic electrolytes composed of an organic
cation and either an organic or inorganic anion, whose melting temperature falls around …

Fundamental importance of ionic interactions in the liquid phase: A review of recent studies of ionic liquids in biomedical and pharmaceutical applications

KS Egorova, VP Ananikov - Journal of Molecular Liquids, 2018 - Elsevier
In recent years, research on ions and ionic interactions in solution has become a leading
scientific direction, and this advance has been especially pronounced in the field of ionic …

Mechanism of antibacterial activity of choline-based ionic liquids (CAGE)

KN Ibsen, H Ma, A Banerjee, EEL Tanner… - ACS Biomaterials …, 2018 - ACS Publications
The continued emergence of antibiotic-resistant organisms has severely depleted our
arsenal of effective antimicrobials. Ionic liquids (ILs) show great promise as antibacterial …

[HTML][HTML] Imidazolium-based ionic liquids cause mammalian cell death due to modulated structures and dynamics of cellular membrane

K Bakshi, S Mitra, VK Sharma, MSK Jayadev… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Here, we report the toxic effects of various imidazolium-based ionic liquids (ILs) with varying
hydrocarbon chain lengths, on different human cell lines. Multiple biological assays have …

Defeat undefeatable: Ionic liquids as novel antimicrobial agents

J Michalski, C Odrzygóźdź, P Mester, D Narożna… - Journal of Molecular …, 2023 - Elsevier
Emerging antimicrobial resistance and spread of drug-resistant pathogens is currently-one
of the biggest threats posed to global health. Due to that, search of new antimicrobials …

Multiscale lipid membrane dynamics as revealed by neutron spectroscopy

VK Sharma, E Mamontov - Progress in Lipid Research, 2022 - Elsevier
The plasma membrane is one of the principal structural components of the cell and,
therefore, one of the key components of the cellular life. Because the membrane's dynamics …

Cholesterol-controlled interaction of ionic liquids with model cellular membranes

P Hitaishi, M Raval, A Seth, S Kumar, VS Mithu… - Langmuir, 2023 - ACS Publications
While ionic liquids (ILs) are considered as prospective ingredients of new antimicrobial
agents, it is important to understand the adverse effects of these molecules on human cells …

Cholesterol protects the liquid-ordered phase of raft model membranes from the destructive effect of ionic liquids

XL Hao, B Cao, D Dai, FG Wu… - The Journal of Physical …, 2022 - ACS Publications
Ionic liquids (ILs), although being a class of promising green solvents, have received many
reports on the toxicity to living organisms. In this work, aiming at elucidating the disruptive …

Room-temperature ionic liquids meet bio-membranes: the state-of-the-art

A Benedetto - Biophysical reviews, 2017 - Springer
Room-temperature ionic liquids (RTIL) are a new class of organic salts whose melting
temperature falls below the conventional limit of 100° C. Their low vapor pressure …

Room-temperature ionic liquids and biomembranes: setting the stage for applications in pharmacology, biomedicine, and bionanotechnology

A Benedetto, P Ballone - Langmuir, 2018 - ACS Publications
Empirical evidence and conceptual elaboration reveal and rationalize the remarkable affinity
of organic ionic liquids for biomembranes. Cations of the so-called room-temperature ionic …