Gallbladder cancer

JC Roa, P García, VK Kapoor, SK Maithel… - Nature reviews Disease …, 2022 - nature.com
Gallbladder cancer (GBC) is the most common cancer of the biliary tract, characterized by a
very poor prognosis when diagnosed at advanced stages owing to its aggressive behaviour …

[HTML][HTML] The versatile emodin: A natural easily acquired anthraquinone possesses promising anticancer properties against a variety of cancers

Q Zhang, WW Chen, X Sun, D Qian… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Cancers are generally recognized as the leading cause of death and a predominant barrier
to prolonging life expectancy in both developed and developing countries. Emodin is a …

IL17 producing γδT cells induce angiogenesis and are associated with poor survival in gallbladder cancer patients

RS Patil, SU Shah, SV Shrikhande… - … journal of cancer, 2016 - Wiley Online Library
Despite conventional treatment modalities, gallbladder cancer (GBC) remains a highly lethal
malignancy. Prognostic biomarkers and effective adjuvant immunotherapy for GBC are not …

Gallbladder cancer: review of a rare orphan gastrointestinal cancer with a focus on populations of New Mexico

JM Nemunaitis, U Brown-Glabeman, H Soares… - BMC cancer, 2018 - Springer
Gallbladder cancer is a rare malignancy of the biliary tract with a poor prognosis, frequently
presenting at an advanced stage. While rare in the United States overall, gallbladder cancer …

Exosomal long non-coding RNA TRPM2-AS promotes angiogenesis in gallbladder cancer through interacting with PABPC1 to activate NOTCH1 signaling pathway

Z He, Y Zhong, P Regmi, T Lv, W Ma, J Wang, F Liu… - Molecular Cancer, 2024 - Springer
Background Abnormal angiogenesis is crucial for gallbladder cancer (GBC) tumor growth
and invasion, highlighting the importance of elucidating the mechanisms underlying this …

UCP2 promotes proliferation and chemoresistance through regulating the NF-κB/β-catenin axis and mitochondrial ROS in gallbladder cancer

J Yu, L Shi, W Lin, B Lu, Y Zhao - Biochemical pharmacology, 2020 - Elsevier
Abstract Uncoupling protein 2 (UCP2) is a mitochondrial anion carrier which plays a key role
in energy homeostasis. UCP2 is deregulated in several human cancers and has been …

Update on chemoresistance mechanisms to first-line chemotherapy for gallbladder cancer and potential reversal strategies

J Lai, S Yang, Z Lin, W Huang, X Li, R Li… - American journal of …, 2023 - journals.lww.com
Objective: Gallbladder cancer (GBC) mortality remains high and chemoresistance is
increasing. This review consolidates what is known about the mechanisms of …

BRD4 inhibitor and histone deacetylase inhibitor synergistically inhibit the proliferation of gallbladder cancer in vitro and in vivo

S Liu, F Li, L Pan, Z Yang, Y Shu, W Lv, P Dong… - Cancer …, 2019 - Wiley Online Library
Gallbladder cancer (GBC) is the most common malignancy of the bile duct and has a high
mortality rate. Here, we demonstrated that BRD 4 inhibitor JQ 1 and histone deacetylase …

[HTML][HTML] MicroRNA aberrations: An emerging field for gallbladder cancer management

V Chandra, JJ Kim, B Mittal, R Rai - World Journal of …, 2016 - ncbi.nlm.nih.gov
Gallbladder cancer (GBC) is infrequent but most lethal biliary tract malignancy characterized
by an advanced stage diagnosis and poor survival rates attributed to absence of specific …

The incidence rates and survival of gallbladder cancer in the USA

V Jaruvongvanich, JD Yang… - European Journal of …, 2019 - journals.lww.com
Gallbladder cancer is a rare malignancy in most countries. The racial and sociodemographic
factors associated with its incidence and survival are poorly defined. We aimed to …