Postoperative pain—from mechanisms to treatment

EM Pogatzki-Zahn, D Segelcke, SA Schug - Pain reports, 2017 - journals.lww.com
Objectives: This review presents and discusses basic science findings and scientific
evidence generated within the last 2 decades in the field of acute postoperative pain …

Advances in assessment of pain behaviors and mechanisms of post-operative pain models

D Segelcke, B Pradier, E Pogatzki-Zahn - Current Opinion in Physiology, 2019 - Elsevier
Each year, more than 300 million surgeries are performed worldwide, which are often
accompanied by postoperative pain. To promote the healing process and prevent …

Transmission pathways and mediators as the basis for clinical pharmacology of pain

DR Kirkpatrick, DM McEntire, TA Smith… - Expert review of …, 2016 - Taylor & Francis
Introduction: Mediators in pain transmission are the targets of a multitude of different
analgesic pharmaceuticals. This review explores the most significant mediators of pain …

Anti-nociceptive effects of magnolol via inhibition of TRPV1/P2Y and TLR4/NF-κB signaling in a postoperative pain model

MI Khan, A Khan, S Zafar, S Aslam, AU Khan, B Shal… - Life Sciences, 2023 - Elsevier
Aims The current study explored the anti-nociceptive activity of magnolol in post-incisional
inflammatory nociceptive pain. Main methods Preliminary, the anti-inflammatory, antioxidant …

Nitric oxide as a messenger between neurons and satellite glial cells in dorsal root ganglia

V Belzer, M Hanani - Glia, 2019 - Wiley Online Library
Abnormal neuronal activity in sensory ganglia contributes to chronic pain. There is evidence
that signals can spread between cells in these ganglia, which may contribute to this activity …

Gene transfer of a naked plasmid (pUDK‐HGF) encoding human hepatocyte growth factor attenuates skin/muscle incision and retraction‐induced chronic post …

C Hu, Y Lu, X Chen, Z Wu, Q Zhang - European Journal of Pain, 2018 - Wiley Online Library
Background Chronic post‐surgical pain (CPSP) remains a major clinical problem and is
often refractory to current treatments. New analgesic medications and strategies for pain …

[PDF][PDF] Experimental models of rheumatoid arthritis: Acute and chronic pain

AM Khanizadeh, F Karimzadeh - The Neuroscience Journal of …, 2017 - shefayekhatam.ir
اب هتخانشان یژولویزیفوتاپ و تلع اب نمزم یباهتلا نمیا دوخ یرامیب نیرت عیاش دیئوتامور
تیرترآ: همدقم زورکن روتکاف لیبق زا ییاه نیکوتیاس حطس رد تارییغت. تسا مدا و یزژلآرپیاه …

Peripheral tetrahydrobiopterin is involved in the pathogenesis of mechanical hypersensitivity in a rodent postsurgical pain model

H Arai, R Takahashi, Y Sakamoto, T Kitano, O Mashita… - Pain, 2020 - journals.lww.com
Because treatment for postsurgical pain (PSP) remains a major unmet medical need, the
emergence of safe and innovative nonopioid drugs has been strongly coveted …

Electroacupuncture Attenuates Inflammatory Pain by Activating AMPK/autophagy and Inhibiting iNOS and IL-1β in Inflamed Tissues

H Xiang, G Cai, L Hu, Y Lan, T Weng, Y Zou, X Yuan… - 2021 - researchsquare.com
Background Electroacupuncture (EA) produces analgesic effects on inflammatory pain
partially via activating adenosine monophosphate (AMP)-activated protein kinase (AMPK) …

مدل‌های آزمایشگاهی آرتریت روماتوئید: درد حاد و مزمن

خانی زاده, کریم زاده - مجله علوم اعصاب شفای خاتم, 2017‎ - shefayekhatam.ir
اب هتخانشان یژولویزیفوتاپ و تلع اب نمزم یباهتلا نمیا دوخ یرامیب نیرت عیاش دیئوتامور
تیرترآ: همدقم زورکن روتکاف لیبق زا ییاه نیکوتیاس حطس رد تارییغت. تسا مدا و یزژلآرپیاه …