Anti-cancer peptide-based therapeutic strategies in solid tumors

M Karami Fath, K Babakhaniyan, M Zokaei… - Cellular & Molecular …, 2022 - Springer
Background Nowadays, conventional medical treatments such as surgery, radiotherapy, and
chemotherapy cannot cure all types of cancer. A promising approach to treat solid tumors is …

Combinatorial peptide libraries: mining for cell-binding peptides

BP Gray, KC Brown - Chemical reviews, 2014 - ACS Publications
The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …

Local triple-combination therapy results in tumour regression and prevents recurrence in a colon cancer model

J Conde, N Oliva, Y Zhang, N Artzi - Nature materials, 2016 - nature.com
Conventional cancer therapies involve the systemic delivery of anticancer agents that
neither discriminate between cancer and normal cells nor eliminate the risk of cancer …

Dual-Color Emissive Upconversion Nanocapsules for Differential Cancer Bioimaging In Vivo

OS Kwon, HS Song, J Conde, H Kim, N Artzi, JH Kim - ACS nano, 2016 - ACS Publications
Early diagnosis of tumor malignancy is crucial for timely cancer treatment aimed at imparting
desired clinical outcomes. The traditional fluorescence-based imaging is unfortunately faced …

Anti‐cancer therapy with TNF α and IFN γ: A comprehensive review

J Shen, Z Xiao, Q Zhao, M Li, X Wu, L Zhang… - Cell …, 2018 - Wiley Online Library
Tumour necrosis factor alpha (TNF α) and interferon gamma (IFN γ) were originally found to
be produced by inflammatory cells and play important roles in the immune system and …

Chemoselective peptide cyclization and bicyclization directly on unprotected peptides

Y Zhang, Q Zhang, CTT Wong, X Li - Journal of the American …, 2019 - ACS Publications
Cyclic peptides are drawing wide attention as potential medium-sized modulators of
biomolecular interactions with large binding surfaces. Simple but effective peptide …

Peptide‐based treatment: a promising cancer therapy

YF Xiao, MM Jie, BS Li, CJ Hu, R Xie… - Journal of …, 2015 - Wiley Online Library
Many new therapies are currently being used to treat cancer. Among these new methods,
chemotherapy based on peptides has been of great interest due to the unique advantages …

Nanotechnology-based intelligent drug design for cancer metastasis treatment

Y Gao, J Xie, H Chen, S Gu, R Zhao, J Shao… - Biotechnology advances, 2014 - Elsevier
Traditional chemotherapy used today at clinics is mainly inherited from the thinking and
designs made four decades ago when the Cancer War was declared. The potency of those …

[HTML][HTML] β-Adrenergic system, a backstage manipulator regulating tumour progression and drug target in cancer therapy

J Tang, Z Li, L Lu, CH Cho - Seminars in cancer biology, 2013 - Elsevier
Abstract β-Adrenoceptors are broadly distributed in various tissues of the body. Stress
hormones regulate a panel of important physiological functions and disease states including …

[HTML][HTML] A single-cell transcriptomic landscape of mouse testicular aging

W Zhang, S Xia, W Xiao, Y Song, L Tang, M Cao… - Journal of Advanced …, 2023 - Elsevier
Introduction Advanced paternal age of reproduction is an increasing trend, especially in
developed countries and areas. This trend results in elevated risks of adverse reproductive …